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Social and Behavioral Sciences Commons

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Full-Text Articles in Social and Behavioral Sciences

Towards A Better Understanding Of Zebrafish Sleep Behavior, Kanza Musarrat Khan May 2017

Towards A Better Understanding Of Zebrafish Sleep Behavior, Kanza Musarrat Khan

Master's Theses

Sleep serves many vital functions in humans, ranging from energy restoration to memory consolidation and information integration. Sleep deprivation is linked to worsened physiological states and psychological conditions. Zebrafish are an emerging model in neurobehavioral research and have recently demonstrated great utility in the study of sleep. This teleost species possesses several of the same neurotransmitter and neuropeptide systems that are involved in the regulation of sleep and waking rhythms in higher order mammals. Previous study of these animals has revealed a differential gene and proteomic expression following sleep deprivation through changes in environmental stimuli. The present study sought to …


Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier May 2017

Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier

Dissertations

Alcohol abuse is the third largest risk factor for disease world, responsible for an estimated 3.3 million deaths each year. The concomitant ingestion of alcohol and caffeine is hypothesized to increase risk factors associated with alcohol use alone by reducing subjective effects of intoxication. The zebrafish (Danio rerio) has recently garnered attention from researchers as an effective pre-clinical in-vivo animal model in behavioral pharmacology research, largely due to small size, low-cost and ease of drug delivery. A number of studies have reported the effects of alcohol and caffeine on zebrafish behavior at a variety of doses. However, the …