Open Access. Powered by Scholars. Published by Universities.®
Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Social and Behavioral Sciences
Toward A Novel Model Of Pain In Zebrafish: Exposure To Water Containing Dilute Concentrations Of Acetic Acid, Amanda D. Currie
Toward A Novel Model Of Pain In Zebrafish: Exposure To Water Containing Dilute Concentrations Of Acetic Acid, Amanda D. Currie
Psychology Honors Projects
Existing models of pain in zebrafish (Danio rerio) require injection of acetic acid into localized areas including the lips. We are currently developing an alternative assay of pain in zebrafish that involves immersion in dilute concentrations of acetic acid. This assay involves placing subjects in a 120 mL beaker containing 100 mL of water taken from the subject’s original tank. After a 20-minute acclimation period, the experimental substances are added, if applicable. Subjects are exposed to the experimental substances for 30 minutes (unless otherwise specified), after which they are returned to their original tanks. A series of studies …