Social and Behavioral Sciences Commons^™

The Moderating Roles Of Racial Discrimination And Covid-19 Stress On The Association Between College Students’ Cannabis Use And Psychosocial Functioning, Shannique Richards

Dissertations and Theses

Abstract

The Moderating Roles of Racial Discrimination and COVID-19 Stress on the Association between College Students’ Cannabis Use and Psychosocial Functioning

By

Shannique Richards, MA

Advisor: Sarah O’Neill, PhD

Greater use of cannabis is linked to poorer psychosocial outcomes. Rates of cannabis use are particularly high in racial/ethnic minoritized (REM) and socioeconomically disadvantaged college students. Cannabis use has been correlated with exposure to trauma. REM and socioeconomically disadvantaged college students report higher rates of trauma exposure, including discrimination and health and social disparities than their White peers. This study examined exposure to two types of potentially traumatic events (racial discrimination …

The Impact Of Cannabis Use On Neuropsychological And Neural Biomarkers Of Treatment Response In Schizophrenia Spectrum Disorders, Melanie B. Thies

Dissertations, Theses, and Capstone Projects

Cannabis use among patients with schizophrenia-spectrum disorders (SSD) is at significantly greater levels than in healthy populations but the impact of cannabis on neural mechanisms of clinical improvement is poorly understood. Cognitive functioning and neural connectivity are disrupted as a result of both SSD and cannabis use, and research indicates that neuropsychological capacity and connectivity of the striatum, a region involved in salience and reward processing, may be integral to effective antipsychotic drug (AP) treatment response. Despite this overlap, no previous research has investigated the effect of cannabis on the brain functions implicated in AP treatment response. The present study …

Analysis Of Cannabinoids In Serum By Gc-Ms/Ms, Christie Cannarozzi

Student Theses

Due to recent changes in federal and state legislations, the availability and consumption of cannabis products have increased in the United States. The expanded use of recreational and medicinal cannabis products increases the importance of implementing sensitive and selective instrumental methods in toxicological laboratories, as legal implications may arise in forensic cases, such as driving under the influence of drugs (DUID). The purpose of this study was to perform a cross-validation for the quantitative analysis of cannabinoids (Δ9-tetrahydrocannabinol, cannabidiol, cannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol, and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol) in serum by gas chromatography coupled to triple quadrupole tandem mass spectrometry (GCTQ). This method was fully …

Locked Out: Thanks To State Policies, Minorities Are Being Left Behind By The Cannabis Industry, Nikitha Sattiraju, Evelina Nedlund

Capstones

Locked Out: Thanks to State Policies, Minorities Are Being Left Behind by the Cannabis Industry

Social justice provisions in states with legal cannabis usually include a percentage of business licenses for minorities and expungements for those formerly incarcerated for cannabis possession so they can participate in the industry. But that isn’t enough for minority communities to successfully start cannabis businesses. Expensive start-up and operation costs, competition from corporate cannabis, lack of banking services for the industry, and fear stemming from decades of over-policing for cannabis use continue to be major roadblocks.

Cannabis legislation across the country is failing to address …

Detection Of In Utero Cannabis Exposure By Umbilical Cord Analysis, Jiyoung Kim

Student Theses

According to 2018 National Survey on Drug Use and Health, 7.1% of pregnant women smoked marijuana in the past month in 2017. Although this prevalence is expected to increase as a growing number of states and countries are now considering legalization, there are scarce data on effects of in utero cannabis exposure. For the monitoring of fetal cannabis exposure, two methods are employed; self-report and the analysis of biological matrix. Due to inaccuracy of self-report, the analysis of neonatal matrixes such as meconium, hair, and urine is perferred. Although umbilical cord is becoming a useful objective tool to detect in …

Quantitative Analysis Of Opioids And Cannabinoids In Wastewater Samples, Alethea Jacox, Jillian Wetzel, Shu-Yuan Cheng, Marta Concheiro-Guisan

Publications and Research

Wastewater-based epidemiology is an innovative approach that uses the analysis of human excretion products in wastewater to obtain information about exposure to drugs in defined population groups. We developed and validated an analytical method for the simultaneous determination of opioids (morphine, oxycodone, hydrocodone, oxymorphone and hydromorphone), and cannabinoids (Δ⁹-tetrahydrocannabinol, 11-nor-9-carboxy-tetrahydrocannabinol (THCCOOH) and THCCOOH-glucuronide) in raw-influent wastewater samples by ultra-high performance liquid chromatography-tandem mass spectrometry. Method validation included linearity (5–1 000 ng/L for opioids, 10–1 000 ng/L for cannabinoids), imprecision (<21.2%), accuracy (83%–131%), matrix effect (from –35.1% to –14.7%) and extraction efficiency (25%–84%), limit of detection (1–5 ng/L) and quantification (5–10 ng/L) and auto-sampler stability (no loss detected). River and wastewater samples were collected in triplicate from different locations in New York City and stored at −20 °C until analysis. Water from sewage overflow location tested positive for morphine (10.7 ng/L), oxycodone (4.2–23.5 ng/L), oxymorphone (4.8 ng/L) and hydromorphone (4.2 ng/L). Raw influent wastewater samples tested positive for morphine (133.0–258.3 ng/L), oxycodone (31.1–63.6 ng/L), oxymorphone (16.0–56.8 ng/L), hydromorphone (6.8–18.0 ng/L), hydrocodone (4.0–12.8 ng/L) and THCCOOH (168.2–772.0 ng/L). This method is sensitive and specific for opioids and marijuana determination in wastewater samples.