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Ultrasensitive Detection Of Antibodies Using A New Tus-Ter-Lock Immunopcr System, Isabelle Morin, Nicholas E. Dixon, Patrick M. Schaeffer
Ultrasensitive Detection Of Antibodies Using A New Tus-Ter-Lock Immunopcr System, Isabelle Morin, Nicholas E. Dixon, Patrick M. Schaeffer
Professor Nick E Dixon
A system consisting of a protein LG coated surface for the capture of mammalian antibodies (target), and an antigen fused to Tus and stoichiometrically linked to a DNA template via the Tus-Ter-lock sequence allowed the ultrasensitive detection of 5.5 attomol of target by real-time immunoPCR in complex media. © The Royal Society of Chemistry 2010.