Social and Behavioral Sciences Commons^™

Factors Associated With The Development Of Depression In Chronic Non-Cancer Pain Patients Following The Onset Of Opioid Treatment For Pain, Kimberley Smith, Richard P. Mattick, Raimondo Bruno, Suzanne Nielsen, Milton Cohen, Gabrielle Campbell, Briony K. Larance, Michael P. Farrell, Louisa Degenhardt

Faculty of Social Sciences - Papers (Archive)

Background and aims Pharmaceutical opioid prescription rates are increasing globally, however knowledge of their long-term effects on mental health, in particular depression remains limited. This study aimed to identify factors associated with the onset of depression post-opioid use that differ to factors associated with depression post-pain. Method Participants (N=1 418) were a national sample prescribed opioids for chronic non-cancer pain. Age at onset of depression, pain and commencement of opioid medications were collected via structured interview. Results Six in 10 (61%) reported lifetime depression; of those, almost half developed depression after pain and after they started opioid medications (48%). Variables …