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Full-Text Articles in Social and Behavioral Sciences
Naturalistic Paradigms For Neuroimaging And Bedside Measures Of Conscious Awareness, Leah J. Sinai
Naturalistic Paradigms For Neuroimaging And Bedside Measures Of Conscious Awareness, Leah J. Sinai
Electronic Thesis and Dissertation Repository
Complex, naturalistic stimuli can test for covert awareness in behaviourally non-responsive patients. For patients with poor visual function, this thesis aimed to identify an auditory-only stimulus that could evaluate executive function. Also, it assessed if Galvanic Skin Response could be a suitable bedside testing method. Healthy individuals listened to 4 auditory stimuli in the fMRI scanner. During Galvanic Skin Response recording, an independent group of controls listened to an audio narrative and watched a movie. Behaviourally non-responsive patients were also tested during movie viewing. Using fMRI, an audio narrative was identified that produced widespread brain synchronization between healthy participants, critically …
Event-Related Potential Markers Of Perceptual And Conceptual Speech Processes In Patients With Disorders Of Consciousness., Stephen T. Beukema
Event-Related Potential Markers Of Perceptual And Conceptual Speech Processes In Patients With Disorders Of Consciousness., Stephen T. Beukema
Electronic Thesis and Dissertation Repository
Vegetative state (VS) and minimally conscious state (MCS) patients behaviorally demonstrate absent or fluctuating levels of awareness. Functional magnetic resonance imaging evidence of covert perceptual and semantic speech processing provides prognostic value for these patients. In this thesis, I examined the utility of high-density electroencephalography (EEG) in this regard. A contrast between event-related potentials (ERPs) elicited by primed and unprimed word pairs was used to isolate conceptual (semantic) processes, while ERPs elicited by signal-correlated noise were contrasted with those elicited by speech to isolate pre-semantic, perceptual aspects of speech processing. These ERP effects were found to be both temporally and …