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Full-Text Articles in Social and Behavioral Sciences
Diffusion Tensor Imaging In Hiv And Hepatitis C Coinfection, Jodi Michelle Heaps
Diffusion Tensor Imaging In Hiv And Hepatitis C Coinfection, Jodi Michelle Heaps
Dissertations
Previous studies have demonstrated that infection with both human immune deficiency virus (HIV) and hepatitis C (HCV) is associated with impaired cognitive function. It is unclear whether co-infection is associated with neuroimaging markers of brain dysfunction. The purpose of the present study was to compare HIV+ individuals, HIV/HCV+ individuals, and seronegative controls using diffusion tensor imaging (DTI) to assess the microstructural integrity of white matter tissue. Methods: Twenty-five HIV+ patients, 25 HIV/HCV+ patients, and 25 seronegative controls matched for age were included in the study. All participants completed an MRI session, neuropsychological testing, and an evaluation of clinical variables including …
Diffusion Tensor Imaging And Neuropsychological Performance In Insulin Resistant Individuals, Elizabeth M. Lane
Diffusion Tensor Imaging And Neuropsychological Performance In Insulin Resistant Individuals, Elizabeth M. Lane
Dissertations
The current study sought to understand relationships between insulin resistance (IR), diffusion tensor imaging (DTI), and cognitive performance. It was hypothesized that IR would have a negative impact upon white matter and cognition. It was predicted that the uncinate fasciculus would be the most severely impacted, and this in turn would affect executive function and memory. Aim: The purpose of the study was to determine the impact of IR on white matter brain integrity among cognitively normal older adults using DTI and neuropsychological test performance. Background: The prevalence of IR has increased with growing incidence of obesity and older aged …