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Full-Text Articles in Social and Behavioral Sciences
Differences In The Prevalence, Severity And Symptom Profiles Of Depression In Boys And Adolescents With An Autism Spectrum Disorder Versus Normally Developing Controls, Vicki Bitsika, Christopher Sharpley
Differences In The Prevalence, Severity And Symptom Profiles Of Depression In Boys And Adolescents With An Autism Spectrum Disorder Versus Normally Developing Controls, Vicki Bitsika, Christopher Sharpley
Vicki Bitsika
The prevalence, severity and symptom profiles for major depressive disorder (MDD) were compared in samples of boys and adolescents with and without an autism spectrum disorder (ASD). Self-reports were obtained on the Depression subscale of the Child and Adolescent Symptoms Inventory (CASI-D) with 70 ASD and 50 non-ASD male participants between the ages of 8 and 18 from Queensland, Australia who were matched for age and IQ. Results indicated that the ASD participants had significantly higher total CASI-D scores, a greater proportion of participants who qualified for a diagnosis of MDD, and over 50% higher scores for 8 of the …
Differences In Neurobiological Pathways Of Four "Clinical Content" Subtypes Of Depression, Christopher Sharpley, Vicki Bitsika
Differences In Neurobiological Pathways Of Four "Clinical Content" Subtypes Of Depression, Christopher Sharpley, Vicki Bitsika
Vicki Bitsika
Although often considered as a mental disorder, depression is best described as a behavioural-neurobiological phenomenon. In addition, although usually reported as a unitary diagnosis, Major Depressive Episode is composed of a range of different symptoms that can occur in nearly 1,500 possible combinations to fulfil the required diagnostic criterion. To investigate and describe the underlying behavioural and neurobiological substrates of these symptoms, they were clustered into "clinical content" subtypes of depression according to their predominant common behavioural characteristics. These subtypes were then found to possess different neurobiological pathways that argue for different treatment approaches.