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Full-Text Articles in Social and Behavioral Sciences
Stress-Induced Attenuation Of Acoustic Startle In Low-Saccharin-Consuming Rats., Clinton Chapman, Mitzi Gonzales, Cameryn Garrett, Nancy Dess
Stress-Induced Attenuation Of Acoustic Startle In Low-Saccharin-Consuming Rats., Clinton Chapman, Mitzi Gonzales, Cameryn Garrett, Nancy Dess
Clinton D Chapman
Exposure to stress can lead to either increased stress vulnerability or enhanced resiliency. Laboratory rats are a key tool in the exploration of basic biobehavioral processes underlying individual differences in the effect of stress on subsequent stressors’ impact. The Occidental low (LoS) and high (HiS) saccharin-consuming rats, which differ in emotional reactivity, are useful in this effort. In the present study, footshock affected acoustic startle amplitude 4h later among LoS but not HiS rats. Surprisingly, shock attenuated startle rather than sensitizing it, a finding not previously reported for male rats exposed to shock. Attenuation was blocked by administering the anxiolytic …
Stress-Induced Attenuation Of Acoustic Startle In Low-Saccharin-Consuming Rats., Clinton Chapman, Nancy Dess, Mitzi Gonzales, Cameryn Garrett
Stress-Induced Attenuation Of Acoustic Startle In Low-Saccharin-Consuming Rats., Clinton Chapman, Nancy Dess, Mitzi Gonzales, Cameryn Garrett
Clinton D Chapman
Exposure to stress can lead to either increased stress vulnerability or enhanced resiliency. Laboratory rats are a key tool in the exploration of basic biobehavioral processes underlying individual differences in the effect of stress on subsequent stressors' impact. The Occidental low (LoS) and high (HiS) saccharin-consuming rats, which differ in emotional reactivity, are useful in this effort. In the present study, footshock affected acoustic startle amplitude 4 h later among LoS but not HiS rats. Surprisingly, shock attenuated startle rather than sensitizing it, a finding not previously reported for male rats exposed to shock. Attenuation was blocked by administering the …