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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
The Design And Progress Of A Multidomain Lifestyle Intervention To Improve Brain Health In Middle-Aged Persons To Reduce Later Alzheimer’S Disease Risk: The Gray Matters Randomized Trial, Maria C. Norton, Christine J. Clark, Joann T. Tschanz, Phillip Hartin, Elizabeth B. Fauth, Julie A. Gast, Travis E. Dorsch, Heidi Wengreen, Chris Nugent, W. David Robinson, Michael Lefevre, Sally Mcclean, Ian Cleland, Sydney Y. Schaefer, Sheryl Aguilar
The Design And Progress Of A Multidomain Lifestyle Intervention To Improve Brain Health In Middle-Aged Persons To Reduce Later Alzheimer’S Disease Risk: The Gray Matters Randomized Trial, Maria C. Norton, Christine J. Clark, Joann T. Tschanz, Phillip Hartin, Elizabeth B. Fauth, Julie A. Gast, Travis E. Dorsch, Heidi Wengreen, Chris Nugent, W. David Robinson, Michael Lefevre, Sally Mcclean, Ian Cleland, Sydney Y. Schaefer, Sheryl Aguilar
Human Development and Family Studies Faculty Publications
Introduction: Most Alzheimer's disease (AD) prevention studies focus on older adults or persons with existing cognitive impairment. This study describes the design and progress of a novel pilot intervention, the Gray Matters study. Methods: This proof-of-concept randomized controlled trial tests an evidence-based multidomain lifestyle intervention in 146 persons aged 40 to 64 years, in northern Utah. Data collectors were blinded to participants' randomization to treatment (n = 104) or control (n = 42). Intervention targeted physical activity, food choices, social engagement, cognitive simulation, sleep quality, and stress management, and uses a custom smartphone application, activity monitor, and educational materials. Secondary …