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Full-Text Articles in Social and Behavioral Sciences
Neuropsychological Correlates Of Anosognosia In Mci And Dementia, Krystle Dina Barrera
Neuropsychological Correlates Of Anosognosia In Mci And Dementia, Krystle Dina Barrera
Loma Linda University Electronic Theses, Dissertations & Projects
Anosognosia is a general term used to describe a lack of awareness of a disability and is well documented in various disorders associated with neurological compromise. While anosognosia is well documented as part and parcel to Alzheimer's dementia, less research has focused on determining the presence of anosognosia in what has come to be viewed as the subclinical precursor to dementia, mild cognitive impairment. In addition, a number of different methodologies and instruments are employed in quantifying and assessing anosognosia in various populations, which make comparison across studies and diagnoses difficult. Research commonly employs a paradigm that uses the discrepancy …
Cognitively Normal Individuals With Ad Parents May Be At Risk For Developing Aging-Related Cortical Thinning Patterns Characteristic Of Ad, Derin J. Cobia, Katherine Reiter, Kathryn I. Alpert, Mary J. Kwasny, John C. Morris, John G. Csernansky, Lei Wang
Cognitively Normal Individuals With Ad Parents May Be At Risk For Developing Aging-Related Cortical Thinning Patterns Characteristic Of Ad, Derin J. Cobia, Katherine Reiter, Kathryn I. Alpert, Mary J. Kwasny, John C. Morris, John G. Csernansky, Lei Wang
Faculty Publications
Children of Alzheimer's Disease (AD) patients are at heightened risk of developing AD due to genetic influences, including the apolipoprotein E4 (ApoE4) allele. In this study, we assessed the earliest cortical changes associated with AD in 71 cognitively healthy, adult children of AD patients (AD offspring) as compared with 69 with no family history of AD (non-AD offspring). Cortical thickness measures were obtained using FreeSurfer from 1.5T magnetic resonance (MR) scans. ApoE genotyping was obtained. Primary analyses examined family history and ApoeE4 effects on cortical thickness. Secondary analyses examined age effects within groups. All comparisons were adjusted using False Discovery …
The Influence Of Widowhood And Sociodemographic Moderators On Dementia And Alzheimer's Disease Risk, Daniel Joseph Hatch
The Influence Of Widowhood And Sociodemographic Moderators On Dementia And Alzheimer's Disease Risk, Daniel Joseph Hatch
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Dementia and Alzheimer’s disease (AD) are dramatic public health problems. In recent years, researchers have uncovered evidence demonstrating that chronic stress can lead to these conditions. Because of this, researchers have also investigated whether widowhood, one of the most stressful life events, may also lead to dementia and AD. However, these studies are conflicting, and few have investigated whether the influence of widowhood on dementia and AD varies in different contexts associated with aging and widowhood. For instance, evidence suggests that widowhood may exert greater influence among males and among those with a history of depression. Other such contextual factors …
Numerical Quantity Estimation In The Elderly, With And Without Cognitive Impairment, Brett Bradley Campbell
Numerical Quantity Estimation In The Elderly, With And Without Cognitive Impairment, Brett Bradley Campbell
Undergraduate Honors Capstone Projects
This study examined mental representation of numerical quantity in 25 elderly participants with varying degrees of cognitive impairment. An analogue number-line task has been used in research of mental representation of numerical quantity in children, but little of such research has been done in elderly populations. This research also examined the clinical utility of this number-line task as a diagnostic tool for dementia and cognitive impairment in old age.
Untangling Cultural Differences In Behavioral, Physiological, And Psychological Symptoms Of Dementia And Alzheimer’S Disease, John S. Avant
Untangling Cultural Differences In Behavioral, Physiological, And Psychological Symptoms Of Dementia And Alzheimer’S Disease, John S. Avant
Calvert Undergraduate Research Awards
According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR; 4th ed. Revised; American Psychiatric Association) and (BPSD) there are many behavioral, physiological, and psychological issues that have been correlated with the progression of the Alzheimer’s disease and other dementias. Examples of these issues include; emotional regulation problems, variations in eating behavior, and an advancing decline in memory. Though certain symptoms of the disease seem to be widely universal, current literature shows that a number of disparities do exist. There are several differences between and within populations suffering from Alzheimer’s disease and dementia that are influenced by various …
Key Predictors Of Well-Being For Individuals With Dementia, Lindsey M. Bisgrove
Key Predictors Of Well-Being For Individuals With Dementia, Lindsey M. Bisgrove
ETD Archive
Until recently, few studies have investigated the psychosocial outcomes of individuals living with dementia. More specifically, the relationship among depression, anxiety, and quality of life as well-being outcomes. The current study examined the role of well-being outcomes and how key predictors (level of cognitive impairment, level of distress experienced, relationship role strain) influenced these outcomes. It addressed how these specific predictors had an impact, on depression and anxiety symptoms and overall quality of life. This study utilized the stress process model for individuals with dementia as a framework to demonstrate the intricacies of the illness experience for the individuals. Self-report …
Semantic Memory Functional Mri And Cognitive Function After Exercise Intervention In Mild Cognitive Impairment, J Carson Smith, Kristy A. Nielson, Piero Antuono, Jeri-Annette Lyons, Ryan J. Hanson, Alissa Butts, Nathan Hantke, Matthew D. Verber
Semantic Memory Functional Mri And Cognitive Function After Exercise Intervention In Mild Cognitive Impairment, J Carson Smith, Kristy A. Nielson, Piero Antuono, Jeri-Annette Lyons, Ryan J. Hanson, Alissa Butts, Nathan Hantke, Matthew D. Verber
Psychology Faculty Research and Publications
Mild cognitive impairment (MCI) is associated with early memory loss, Alzheimer's disease (AD) neuropathology, inefficient or ineffective neural processing, and increased risk for AD. Unfortunately, treatments aimed at improving clinical symptoms or markers of brain function generally have been of limited value. Physical exercise is often recommended for people diagnosed with MCI, primarily because of its widely reported cognitive benefits in healthy older adults. However, it is unknown if exercise actually benefits brain function during memory retrieval in MCI. Here, we examined the effects of exercise training on semantic memory activation during functional magnetic resonance imaging (fMRI). Seventeen MCI participants …
An Acute Inflammatory Response In A Diabetic Alzheimer’S Disease Model, Krystal Courtney D. Belmonte, Jefferson Kinney
An Acute Inflammatory Response In A Diabetic Alzheimer’S Disease Model, Krystal Courtney D. Belmonte, Jefferson Kinney
McNair Poster Presentations
Alzheimer’s disease (AD) is the most common form of dementia, accounting for 50 to 80 percent of all dementia cases. This neurodegenerative disease leads to neuronal death and tissue loss in the brain, resulting in the slow deterioration of memory, thinking skills, and eventually even the ability perform daily tasks. While it is not a normal part of aging, AD is mostly diagnosed in people over the age of 65; thus, the main risk factor for Alzheimer’s disease is increased age, though it is most likely other additional factors also contribute (Heese & Akatsu, 2006). Neuropathological hallmarks of AD include …