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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Network Analysis Of Cognitive Symptom Domains In Alzheimer's Disease (Ad), Abigail Rose Baily
Network Analysis Of Cognitive Symptom Domains In Alzheimer's Disease (Ad), Abigail Rose Baily
UNLV Theses, Dissertations, Professional Papers, and Capstones
Alzheimer’s Disease (AD) is a degenerative neurological disease process that results in cognitive and functional declines and ultimately results in death. The pattern and course of cognitive and functional decline has been well characterized in AD, however little is known about the interactions between the symptoms. Network Analysis is a recently developed mathematical approach of examining the interactions between symptoms, by exploring the covariance of symptoms. The current study utilized network analysis to examine the multivariate structural dependencies among cognitive domains known to be affected in Alzheimer’s disease. The sample consisted of 864 older adults (60-90 years old), selected from …
Continuous Theta Rhythm During Spatial Working Memory Task In Rodent Models Of Streptozotocin-Induced Type 2 Diabetes, Stephanie Hernandez, Ryan A. Wirt, James M. Hyman
Continuous Theta Rhythm During Spatial Working Memory Task In Rodent Models Of Streptozotocin-Induced Type 2 Diabetes, Stephanie Hernandez, Ryan A. Wirt, James M. Hyman
McNair Poster Presentations
Alzheimer’s disease is a neurodegenerative disorder altering memory loss thought to be due to neuropathological symptoms such as the buildup of beta amyloid plaques (Ab) and neurofibrillary tangles (NFT). The etiology of Alzheimer’s is still unknown; however, potential risk factors such as diabetes may lead to its development. The most common form of diabetes is type 2 diabetes known for persistent insulin resistance leading to a state of hyperglycemia. Insulin resistance has been shown to affect cognitive abilities such as learning, memory and also alters synaptic plasticity. Neural connections between the hippocampus (HC) and anterior cingulate cortex (ACC) are known …