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Full-Text Articles in Social and Behavioral Sciences

Examining Four Blood Biomarkers For The Detection Of Acute Intracranial Abnormalities Following Mild Traumatic Brain Injury In Older Adults, Grant L. Iverson, Mira Minkkinen, Justin E. Karr, Ksenia Berghem, Henrik Zetterberg, Kaj Blennow, Jussi P. Posti, Teemu M. Luoto Nov 2022

Examining Four Blood Biomarkers For The Detection Of Acute Intracranial Abnormalities Following Mild Traumatic Brain Injury In Older Adults, Grant L. Iverson, Mira Minkkinen, Justin E. Karr, Ksenia Berghem, Henrik Zetterberg, Kaj Blennow, Jussi P. Posti, Teemu M. Luoto

Psychology Faculty Publications

Blood-based biomarkers have been increasingly studied for diagnostic and prognostic purposes in patients with mild traumatic brain injury (MTBI). Biomarker levels in blood have been shown to vary throughout age groups. Our aim was to study four blood biomarkers, glial fibrillary acidic protein (GFAP), ubiquitin C-terminal hydrolase-L1 (UCH-L1), neurofilament light (NF-L), and total tau (t-tau), in older adult patients with MTBI. The study sample was collected in the emergency department in Tampere University Hospital, Finland, between November 2015 and November 2016. All consecutive adult patients with head injury were eligible for inclusion. Serum samples were collected from the enrolled patients, …


Alcohol Use, Sleep, And Depression Among Family Caregivers In The Time Of Covid-19, Ashley M. Strzelecki, Mairead E. Moloney, Alyssa T. Brooks, Jessica Weafer Aug 2022

Alcohol Use, Sleep, And Depression Among Family Caregivers In The Time Of Covid-19, Ashley M. Strzelecki, Mairead E. Moloney, Alyssa T. Brooks, Jessica Weafer

Psychology Faculty Publications

The COVID-19 pandemic has substantially altered daily life around the world, resulting in significant impacts on health behaviors. The additional burdens imposed by family caregiving (i.e., providing unpaid care for children and/or adults) may further exacerbate negative effects of the pandemic on health and health behaviors, including increased alcohol consumption, poor sleep, and increased depressive symptoms. The current study examined this possibility. Participants (N = 320, mean age = 35.11 years) completed an online questionnaire assessing alcohol use, sleep, and depression during the COVID-19 pandemic (June–August 2020) and retrospectively assessed the same health behaviors in the months prior to the …


Differences In Distress Between Rural And Non-Rural Appalachian Breast Cancer Patient / Caregiver Dyads During The First Year Of Treatment, Jordan Tasman, Callie D. Mcadams, Jillian Lloyd, Ashton J. Brooks, Patricia Nola Eugene Roberson Mar 2022

Differences In Distress Between Rural And Non-Rural Appalachian Breast Cancer Patient / Caregiver Dyads During The First Year Of Treatment, Jordan Tasman, Callie D. Mcadams, Jillian Lloyd, Ashton J. Brooks, Patricia Nola Eugene Roberson

Journal of Appalachian Health

Introduction: Breast cancer patients and their caregivers living in rural Appalachia face substantial health disparities compared to their non-rural Appalachian counterparts. However, there is limited research on how these specific health disparities in rural Appalachian communities may impact patient psychological distress and caregiver strain during the first year of breast cancer treatment.

Purpose: The purpose of the current study was to assess differences in patient psychological distress (depression and anxiety) and caregiver strain between rural non-rural Appalachian breast-cancer-affected dyads (patients and their caregivers) during the first year of treatment.

Methods: A total of 48 Appalachian breast cancer patients (with a …


Editorial: Individual Differences In Cognition And Affects In The Era Of Pandemic And Machine Learning, Andrea Vranic, Yang Jiang, Xiaopeng Zhao Feb 2022

Editorial: Individual Differences In Cognition And Affects In The Era Of Pandemic And Machine Learning, Andrea Vranic, Yang Jiang, Xiaopeng Zhao

Behavioral Science Faculty Publications

No abstract provided.


A Cluster Randomized Controlled Trial For A Multi-Level, Clinic-Based Smoking Cessation Program With Women In Appalachian Communities: Study Protocol For The "Break Free" Program, Joanne G. Patterson, Tia N. Borger, Jessica L. Burris, Mark Conaway, Robert Klesges, Amie Ashcraft, Lindsay Hauser, Connie Clark, Lauren Wright, Sarah Cooper, Merry C. Smith, Mark B. Dignan, Stephenie Kennedy-Rea, Electra D. Paskett, Roger Anderson, Amy K. Ferketich Feb 2022

A Cluster Randomized Controlled Trial For A Multi-Level, Clinic-Based Smoking Cessation Program With Women In Appalachian Communities: Study Protocol For The "Break Free" Program, Joanne G. Patterson, Tia N. Borger, Jessica L. Burris, Mark Conaway, Robert Klesges, Amie Ashcraft, Lindsay Hauser, Connie Clark, Lauren Wright, Sarah Cooper, Merry C. Smith, Mark B. Dignan, Stephenie Kennedy-Rea, Electra D. Paskett, Roger Anderson, Amy K. Ferketich

Psychology Faculty Publications

BACKGROUND: The cervical cancer burden is high among women living in Appalachia. Cigarette smoking, a cervical cancer risk factor, is also highly prevalent in this population. This project aims to increase smoking cessation among women living in Appalachia by embedding a smoking cessation program within a larger, integrated cervical cancer prevention program.

METHODS: The broader program, the Take CARE study, is a multi-site research collaborative designed to address three risk factors for cervical cancer incidence and mortality: tobacco use, human papillomavirus (HPV) infection, and cervical cancer screening. Break Free is a primary care clinic-based implementation program that aims to promote …


Choice Bundling Increases Valuation Of Delayed Losses More Than Gains In Cigarette Smokers, Jeffrey S. Stein, Jeremiah M. Brown, Allison N. Tegge, Roberta Freitas-Lemos, Mikhail N. Koffarnus, Warren K. Bickel, Gregory J. Madden Jan 2022

Choice Bundling Increases Valuation Of Delayed Losses More Than Gains In Cigarette Smokers, Jeffrey S. Stein, Jeremiah M. Brown, Allison N. Tegge, Roberta Freitas-Lemos, Mikhail N. Koffarnus, Warren K. Bickel, Gregory J. Madden

Family and Community Medicine Faculty Publications

Choice bundling, in which a single choice produces a series of repeating consequences over time, increases valuation of delayed monetary and non-monetary gains. Interventions derived from this manipulation may be an effective method for mitigating the elevated delay discounting rates observed in cigarette smokers. No prior work, however, has investigated whether the effects of choice bundling generalize to reward losses. In the present study, an online panel of cigarette smokers (N = 302), recruited using survey firms Ipsos and InnovateMR, completed assessments for either monetary gains or losses (randomly assigned). In Step 1, participants completed a delay-discounting task to …


Applications Of The John Henryism Hypothesis: Mitigating Associations Between Incarceration, Drug Use, And Sex Partner Characteristics, Paris Wheeler Jan 2022

Applications Of The John Henryism Hypothesis: Mitigating Associations Between Incarceration, Drug Use, And Sex Partner Characteristics, Paris Wheeler

Theses and Dissertations--Educational, School, and Counseling Psychology

Individual risk behaviors are not enough to explain STI disparities among African American women. Effects of structural, social, and individual level risk factors may be mitigated by cultural factors that help increase resilience. The current study aimed to examine whether John Henryism Active Coping (JHAC), a cultural correlate marked by physical and mental vigor and self-determination, mitigates relationships between criminal justice status, crack cocaine use, and sex partner risk characteristics. Data were derived from a sample of African American women living in Kentucky (n=643). Ordinal logistic regression and stepwise linear regression analyses were utilized to examine whether interactions between criminal …


Juror Perceptions Of Heterosexual And Same-Sex Spousal Rape In The Courtroom, Haley D. Hintz Jan 2022

Juror Perceptions Of Heterosexual And Same-Sex Spousal Rape In The Courtroom, Haley D. Hintz

Lewis Honors College Thesis Collection

Approximately 10-15% of American women will be raped by a spouse in their lifetime (Bureau of Justice Statistics, 2002). Research suggests that the American public regards spousal rape as wrong but not rape (Lynch et al., 2017). Research on spousal rape has centered on heterosexual couples despite a higher likelihood that LGBTQ+ individuals will experience severe intimate partner violence (IPV) (Rollé et al., 2019). Therefore, the present study investigated mock juror perceptions of spousal rape of heterosexual and same-sex couples in the courtroom. We employed a 2 (victim gender) x 2 (defendant gender) x 2 (participant gender) between-participants design. Participants …


Pain Interference Across Chronic Pain Populations: Variability And Associated Psychosocial Processes, Stephanie Judge Jan 2022

Pain Interference Across Chronic Pain Populations: Variability And Associated Psychosocial Processes, Stephanie Judge

Theses and Dissertations--Psychology

Chronic pain is one of the most common health complaints, yet the limited effectiveness of existing treatment options suggests that chronic pain is still not fully understood. The goals of this study are to identify and organize well-established and emerging psychosocial factors associated with pain interference, clarify the nature of between- and within-diagnostic group differences in psychosocial and demographic factors associated with pain interference, and identify interactions among diagnostic and psychosocial factors associated with pain interference.

Community-dwelling participants (N = 284) completed a one-time survey which included demographic information, information about pain and diagnosis, and five existing measures that assess …


Feedback For Teachers: What Evidence Do Teachers Find Most Useful?, Thomas R. Guskey, Laura J. Link Jan 2022

Feedback For Teachers: What Evidence Do Teachers Find Most Useful?, Thomas R. Guskey, Laura J. Link

Educational, School, and Counseling Psychology Faculty Publications

The purpose of this exploratory, descriptive study was to investigate teachers’ perceptions of three types of feedback on students’ performance to guide instructional improvements. These include: (1) formative assessment error analyses, (2) mastery charts of class progress on formative assessments, and (3) summative assessment results comparisons with previously taught classes. Self-report survey data from 92, K-12 teachers involved in a pilot mastery learning program revealed that analyses of students’ errors on formative assessments were consistently rated the most useful in planning corrective instruction and in making instructional improvements. Mastery charts and summative assessment results were considered more useful in evaluating …


Early Maturing Out Of Problematic Alcohol Use, Sarah J. Peterson Jan 2022

Early Maturing Out Of Problematic Alcohol Use, Sarah J. Peterson

Theses and Dissertations--Psychology

Most research suggests that alcohol use peaks in the college years then declines into the mid-thirties (Jochman & Fromme, 2010). However, there is evidence that some individuals mature out earlier: downward trends for some individuals begin in college, with as many as one third of students decreasing their drinking (Baer et al., 2001). It is crucial to identify factors that differentiate those who decrease their drinking early from those who persist in high levels of consumption; doing so would clarify risk for college-related alcohol problems and perhaps subsequent alcohol use disorder, and aid in earlier targeted prevention and intervention. This …


Mental Health In The Courtroom: How Victim Mental Illness Impacts Juror Decision-Making In A Rape Case, Mary M. Levi Jan 2022

Mental Health In The Courtroom: How Victim Mental Illness Impacts Juror Decision-Making In A Rape Case, Mary M. Levi

Theses and Dissertations--Psychology

The influence of mental illness on jury decision-making has rarely been investigated, and even fewer studies have examined how jurors perceive a victim with mental illness. The present study investigated the effect of victim mental illness on jury decision-making in a rape trial using a 3 (victim mental health status: schizophrenia, depression, no illness) x 2 (participant gender: female, male) between-subjects design. I hypothesized that mock jurors would render fewer guilty verdicts in the schizophrenia condition compared to the depression condition, and render fewer guilty verdicts in the schizophrenia and depression conditions compared to the control. I also hypothesized that …


Experiential-Based Feedback During Alcohol Intoxication And Its Effect On Drinkers’ Risk Awareness, Alexandra R. Kelly Jan 2022

Experiential-Based Feedback During Alcohol Intoxication And Its Effect On Drinkers’ Risk Awareness, Alexandra R. Kelly

Theses and Dissertations--Psychology

The prevalence of alcohol-impaired driving injuries and fatalities has not decreased for over a decade despite strategies to reduce and prevent driving under the influence of alcohol (DUI). In 2019, 10,142 people died in alcohol-impaired driving crashes in the United States, which totaled to 28% of all traffic fatalities for the year. DUI interventions have been found to have moderate effects on reducing DUI recidivism. Prevention research has identified a lack of risk awareness in DUI offenders and this could be a target to motivate behavioral change. However, the training to increase levels of risk awareness needs to occur in …


"Think Of The Situation In A Positive Light": A Look At Cognitive Reappraisal, Affective Reactivity And Health, Jessica Chloe Maras Jan 2022

"Think Of The Situation In A Positive Light": A Look At Cognitive Reappraisal, Affective Reactivity And Health, Jessica Chloe Maras

Theses and Dissertations--Psychology

How individuals regulate their emotions is critical for maintaining health and well-being. For example, reframing a stressful situation in a positive light, a form of cognitive reappraisal, is beneficial for health and well-being outcomes. However, it is currently unclear why this relationship exists. One potential mechanism could be how one emotionally reacts to stressors in daily life, termed affective reactivity. The current study examined longitudinal associations that spanned 20 years between cognitive reappraisal and health outcomes and subjective well-being and if affective reactivity mediated this relationship. Participants completed waves 1-3 of the Midlife in the United States (MIDUS) Survey series …


Meeting The Psychosocial Needs Of Online Learners In Social Work Programs And Four-Year Universities: What Is Being Addressed And The Many Areas For Improvement, Kathryn Gould Jan 2022

Meeting The Psychosocial Needs Of Online Learners In Social Work Programs And Four-Year Universities: What Is Being Addressed And The Many Areas For Improvement, Kathryn Gould

DSW Capstone Projects

Almost half of social work students enter their program with a history of mental health diagnosis and exposure to multiple childhood traumas. Over half of students at four-year institutions are enrolled in one or more courses online, yet retention in online coursework is much lower than in in-person courses. As online programs continue to grow in the field of social work it becomes a vital requirement to address the psychosocial needs of online learners. The call of this capstone is to examine how universities and colleges of social work can meet the increasing need to improve course work and service …


A Pathway For Inclusive Innovation In Pediatric Mental Health: Prevention And Intervention Using Technology, Kate Corinne Bennett Jan 2022

A Pathway For Inclusive Innovation In Pediatric Mental Health: Prevention And Intervention Using Technology, Kate Corinne Bennett

DSW Capstone Projects

It is no secret that access to quality healthcare is difficult for citizens to achieve in the United States. Racism, discrimination, and oppression further exist at the root of compounding social problems, including limits in minority access to mental health services. The COVID-19 pandemic has also exacerbated mental health problems for young children, especially those who are already underserved and at risk. For these reasons, it is imperative that the social work profession emphasizes innovative approaches to equitable treatment access, including a focus on early intervention and the use of technology. Product one of this capstone engages a systematic review …


Clinical Interventions For Developmental Trauma Disorder: How Evidence-Based Practice And Attachment Theory Can Inform Therapeutic Approach, Victoria Deveau Jan 2022

Clinical Interventions For Developmental Trauma Disorder: How Evidence-Based Practice And Attachment Theory Can Inform Therapeutic Approach, Victoria Deveau

DSW Capstone Projects

Approximately two-thirds of U.S. children and adolescents report having experienced a traumatic event. A posttraumatic stress disorder (PTSD) diagnosis requires that the youth has directly experienced a traumatic event, witnessed a traumatic event occur to others, or learned that a traumatic event has occurred to someone close. The clinician is in a diagnostic quandary, however, when the youth presents with the PTSD hallmarks of hyperarousal, avoidance, and emotional dysregulation, in absence of such life experiences. The answer to this quandary lies in an understanding of developmental trauma disorder (DTD). Clinical interventions for DTD are the focus of this capstone.

Product …


Appalachians’ Intentions To Use Online And In-Person Counseling, Jade Hollan Jan 2022

Appalachians’ Intentions To Use Online And In-Person Counseling, Jade Hollan

Theses and Dissertations--Educational, School, and Counseling Psychology

Appalachians face higher rates of mental health concerns, yet they are less likely to have access to quality treatment. Online counseling, counseling using videoconferencing technology, may provide a viable solution to narrow this gap. However, little is known about Appalachians’ intention to use in-person or online counseling. This study examined Appalachians’ (N = 490) intentions to use online and in-person counseling using the theoretical framework of Theory of Planned Behavior (TPB; Ajzen, 1991). Results from structural equation modeling supported the indirect model for online and in-person counseling, where the associations between distal help-seeking factors (i.e., self-stigma, perceived stigma of …


“Don’T Feel Like You Have To Do This All On Your Own”: Exploring Perceived Partner Support Of Breastfeeding Among Black Women In Kentucky, Jardin Dogan Jan 2022

“Don’T Feel Like You Have To Do This All On Your Own”: Exploring Perceived Partner Support Of Breastfeeding Among Black Women In Kentucky, Jardin Dogan

Theses and Dissertations--Educational, School, and Counseling Psychology

Background: Partner support improves breastfeeding initiation and continuation among mothers. However, few studies have explored partner support for breastfeeding among Black women living in the southeastern U.S., who report the lowest rates nationally of breastfeeding compared to women of other racial groups. Ways to increase support of Black women’s breastfeeding may be best understood from an Afrocentric perspective.

Research Aim: This qualitative study aimed to explore perceptions of partner support among Black mothers to abductively develop a culturally relevant framework of partner support to improve their rates of breastfeeding. Our research question was, “What partner support behaviors do Black …


A Content Analysis Of Reddit Comments Discussing Fibroadenoma Appraisal And Decision Making, Hayley Marie Kay Stahl Jan 2022

A Content Analysis Of Reddit Comments Discussing Fibroadenoma Appraisal And Decision Making, Hayley Marie Kay Stahl

Theses and Dissertations--Communication

Though fibroadenomas are clinically benign in most cases, clinical research suggests that these lesions can cause diagnosis-related physical health complications and psychological distress. However, this research is limited and should be investigated further. Thus, this study aimed to explore how patients appraise their fibroadenoma diagnosis uncertainty. Additionally, this study sought to determine if a correlation existed between appraisal and decision making as well as identify the factors that influence the most common treatment decision: removal. Data was retrieved from Reddit discussions for a content analysis. These discussions were then qualitatively analyzed using codebooks associated with this study’s research questions. Findings …


Effects Of An Online Insomnia Intervention On Sleep And Alcohol Consumption, Justin Verlinden Jan 2022

Effects Of An Online Insomnia Intervention On Sleep And Alcohol Consumption, Justin Verlinden

Theses and Dissertations--Psychology

Alcohol use disorder (AUD) and insomnia are highly comorbid, due in part to the use of alcohol as a sleep aid among individuals with insomnia. Initial studies have shown that cognitive behavioral therapy for insomnia (CBT-I), the first-line treatment for insomnia, is moderately successful at improving both sleep and drinking outcomes in heavy drinkers with insomnia. However, CBT-I is expensive and not widely available. Online CBT-I could be a more accessible alternative. One online CBT-I program, Sleep Healthy Using the Internet (SHUTi), is especially promising due to its high efficacy in treating insomnia and its individualized and interactive platform. Here …


Promotion Of Early Recognition Of Depression To Improve Health Related Quality Of Life In Pediatric Oncology Patients, Jennifer Blankenship Jan 2022

Promotion Of Early Recognition Of Depression To Improve Health Related Quality Of Life In Pediatric Oncology Patients, Jennifer Blankenship

DNP Projects

Background: Depression and anxiety are serious complications of cancer and deemed a challenging diagnosis due to the symptoms of depression mimicking common side effects of chemotherapy and radiation. Signs/symptoms frequently are underrecognized thus appropriate treatment is delayed, compromising the health-related quality of life (HRQOL) for pediatric oncology patients.

Purpose: Analyze existing physician and Advanced Practice Provider (APP) clinical practice regarding depression, via a pre- and post-survey and educational PowerPoint on the use of the Center for Epidemiological Studies Depression Scale for Children (CES-DC) to promote early recognition of depression.

Methods: A prospective, single-arm, study was completed in the Kentucky Children’s …


An Overview Of Functional Communication Training For Registered Behavior Technicians, Christopher Dollinger Jan 2022

An Overview Of Functional Communication Training For Registered Behavior Technicians, Christopher Dollinger

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

Functional Communication Training (FCT) is an intervention involving the differential reinforcement of an alternative response (DRA), in which an appropriate communicative response (e.g., asking for a break) is reinforced while the behavior targeted for decrease (e.g., hitting to get out of work) has reinforcement withheld in its presence. Individuals who work as registered behavior technicians (RBT), under the supervision of a board-certified behavior analyst (BCBA), may implement FCT daily. With that being said, many individuals who choose to work as an RBT may not have as deep of an understanding of the concepts and principles of applied behavior analysis (ABA) …


Examining The Indirect Effect Of Trauma On Obsessive-Compulsive Symptoms Through Responsibility/Threat Beliefs, Emily E. Fenlon Jan 2022

Examining The Indirect Effect Of Trauma On Obsessive-Compulsive Symptoms Through Responsibility/Threat Beliefs, Emily E. Fenlon

Theses and Dissertations--Psychology

Inflated responsibility beliefs and threat estimations have been implicated in the etiology and maintenance of obsessive-compulsive (OC) symptoms. Research suggests that early life experiences that involve actual or perceived serious harm to oneself or others may lead to inflated responsibility/threat beliefs and OC symptoms. Research has yet to explore if traumatic experiences influence responsibility/threat beliefs or if the associations between trauma and OC symptoms are at all dependent on trauma’s influence on responsibility/threat beliefs. The present study aims to examine associations among exposure to potentially traumatic events (PTEs), responsibility/threat beliefs, and OC symptoms. A sample of 886 undergraduate students completed …


Turning The Tides: An Inoculation Theory And Theory Of Planned Behavior Approach To Developing Mental Health Help-Seeking Interventions For Gen Z, Sarah Ann Geegan Jan 2022

Turning The Tides: An Inoculation Theory And Theory Of Planned Behavior Approach To Developing Mental Health Help-Seeking Interventions For Gen Z, Sarah Ann Geegan

Theses and Dissertations--Communication

Extensive research, predating and during the COVID-19 pandemic, demonstrates the rising prevalence of anxiety and depression among Gen Z college students in the United States—findings which are accompanied by rising rates of suicide, the second leading cause of death among people aged 15-24. Although college campuses often offer mental health resources, the number of college students utilizing them is significantly less than the number of students reporting mental health challenges. A dearth of empirical evidence, focused on Gen Z specifically, exists as a basis for developing interventions to address this issue. This investigation addressed this gap through two component studies. …


Latent Classes Of Symptom Trajectory In A Brief Treatment For Borderline Personality Disorder, Doug Terrill Jan 2022

Latent Classes Of Symptom Trajectory In A Brief Treatment For Borderline Personality Disorder, Doug Terrill

Theses and Dissertations--Psychology

It is likely that patients with BPD progress through treatment in different ways. Characterizing symptom trajectories during treatment can facilitate the identification of distinct treatment responses, which may be shared by subgroups of patients. Researchers have consistently identified multiple distinct symptom trajectories among individuals with common psychopathological conditions, but no research to date has attempted to do so among patients with BPD. This study used latent growth mixture modeling to identify and characterize distinct classes of symptom trajectories among patients receiving an 18-week cognitive-behavioral treatment for BPD. Two distinct BPD symptom trajectories were identified in this sample, which were primarily …


How To Live Life All The Way Up Learning Life Skills From Literary Characters, Sue N. Mize Jan 2022

How To Live Life All The Way Up Learning Life Skills From Literary Characters, Sue N. Mize

Theses and Dissertations--English

In this essay, using the theories of psychiatrist, Eric Berne and his script theory; psychoanalyst, Carl Jung and his archetypes and mandalas; as well as the Native American Medicine Wheel; and the Hindu notion of the kundalini, I analyze the psychological development of Adele Quested of E.M. Forster’s A Passage to India (1924) and Anna Wulf of Doris Lessing’s The Golden Notebook (1962). Adela Quested goes to India seeking the real India and while engaging the archetype of the Lover discovers her real Self. While in India she metaphorically walks the Medicine Wheel and discovers that to be …


Increasing Accuracy In Police Report Writing, Zachary Greene Jan 2022

Increasing Accuracy In Police Report Writing, Zachary Greene

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

The current alternative thesis project consisted of creating an online learning course intended to increase the accuracy with which preservice and in-service police officers write police incident reports. The online course consists of 6 separate modules and utilizes principles of applied behavior analysis (ABA) to assist the learner in understanding and applying the content of the modules. Specifically, components of interactive computer training (ICT), consisting of video modeling, voice over narration, interactive activities, and self-pace module design were implemented in the design of the learning course. Opportunities throughout the course allow the learner to self-reflect, self-assess, and receive feedback.


Blocking The Acquisition Of Ethanol-Induced Conditioned Place Preference With 11, 21-Bisphenyl-19-Norpregnane (Pt150) In Coturnix Quail, Mia Radevski Jan 2022

Blocking The Acquisition Of Ethanol-Induced Conditioned Place Preference With 11, 21-Bisphenyl-19-Norpregnane (Pt150) In Coturnix Quail, Mia Radevski

Theses and Dissertations--Psychology

Alcohol use disorder (AUD) has been associated with a dysregulated stress system. Therefore, regulating stress hormones has been investigated as a potential therapeutic target for AUDs. The purpose of the current study was to investigate whether a stress hormone receptor antagonist, PT150, would block the rewarding properties of ethanol. Quail were used as subjects because a conditioned place preference (CPP) apparatus that utilized visual cues was used, and quail readily attend to visual cues. Visual cues in the environment have been shown to become associated with alcohol effects and later induce craving. Starting on day one, quail were pretreated with …


Investigating Mechanisms Of Injury And Intervention In A Novel In Vitro Model Of Traumatic Brain Injury In Organotypic Hippocampal Slice Cultures, Julia Elaine Jagielo-Miller Jan 2022

Investigating Mechanisms Of Injury And Intervention In A Novel In Vitro Model Of Traumatic Brain Injury In Organotypic Hippocampal Slice Cultures, Julia Elaine Jagielo-Miller

Theses and Dissertations--Psychology

Traumatic brain injuries (TBIs) impact millions of individuals each year and can pose long term consequences. Despite numerous attempts, no medication has been approved by the FDA to treat TBIs. The causes of these failed trials are multifaceted, but in part can be attributed to the complex nature of TBIs, as well as a lack of sufficient pre-clinical data. In vitro models of TBI are an important tool to help understand the cellular changes seen following the injury, in a highly controlled environment. For the following experiments, a novel model of TBI was used to injure organotypic hippocampal slice cultures, …