Social and Behavioral Sciences Commons^™

Long-Term Outcomes Of Behavior Therapy For Youth With Tourette Disorder, Flint M. Epsil, Douglas W. Woods, Matthew W. Specht, Shannon M. Bennett, John T. Walkup, Emily J. Ricketts, Joseph F. Mcguire, Jordan T. Stiede, Jennifer S. Schild, Susanna W. Chang, Alan L. Peterson, Lawrence Scahill, Sabine Wilhelm, John Piacentini

Psychology Faculty Research and Publications

Objective

To determine the long-term durability of behavior therapy for tics among youth with Tourette disorder and persistent (chronic) motor or vocal tic disorders.

Method

Of the 126 youth who participated in a randomized controlled trial of behavior therapy 11 years prior, 80 were recruited for this longitudinal follow-up. Consenting participants were interviewed in person or remotely (Web-based video) by trained evaluators to determine the course of tics, current tic severity, and tic-related impairment. Recruitment and data collection occurred between 2014 and 2019, with an average follow-up duration of 11.2 years.

Results

Treatment responders to both conditions in the original …

Pediatric Prevention: Tic Disorders, Jordan T. Stiede, Douglas W. Woods

Psychology Faculty Research and Publications

No abstract provided.

Investigating Habituation To Premonitory Urges In Behavior Therapy For Tic Disorders, David C. Houghton, Matthew R. Capriotti, Lawrence Scahill, Sabine Wilhelm, Alan L. Peterson, John T. Walkup, John Piacentini, Douglas W. Woods

Psychology Faculty Research and Publications

Behavior therapy is effective for Persistent Tic Disorders (PTDs), but behavioral processes facilitating tic reduction are not well understood. One process, habituation, is thought to create tic reduction through decreases in premonitory urge severity. The current study tested whether premonitory urges decreased in youth with PTDs (N = 126) and adults with PTDs (N = 122) who participated in parallel randomized clinical trials comparing behavior therapy to psychoeducation and supportive therapy (PST). Trends in premonitory urges, tic severity, and treatment outcome were analyzed according to the predictions of a habituation model, whereby urge severity would be expected to …

Moderators And Predictors Of Response To Behavior Therapy For Tics In Tourette Syndrome, Denis G. Sukhodolsky, Douglas W. Woods, John Piacentini, Sabine Wilhelm, Alan L. Peterson, Lily Katsovich, James Dziura, John T. Walkup, Lawrence Scahill

Psychology Faculty Research and Publications

Objective: To examine moderators and predictors of response to behavior therapy for tics in children and adults with Tourette syndrome and chronic tic disorders.

Methods: Data from 2 10-week, multisite studies (1 in children and 1 in adults; total n = 248) comparing comprehensive behavioral intervention for tics (CBIT) to psychoeducation and supportive therapy (PST) were combined for moderator analyses. Participants (177 male, 71 female) had a mean age of 21.5 ± 13.9 years (range 9–69). Demographic and clinical characteristics, baseline tic-suppressing medication, and co-occurring psychiatric disorders were tested as potential moderators for CBIT vs PST or predictors of outcome …

Comparing Fixed-Amount And Progressive-Amount Dro Schedules For Tic Suppression In Youth With Chronic Tic Disorders, Matthew R. Capriotti, Jennifer E. Turkel, Rachel A. Johnson, Flint M. Espil, Douglas W. Woods

Psychology Faculty Research and Publications

Chronic tic disorders (CTDs) involve motor and/or vocal tics that often cause substantial distress and impairment. Differential reinforcement of other behavior (DRO) schedules of reinforcement produce robust, but incomplete, reductions in tic frequency in youth with CTDs; however, a more robust reduction may be needed to affect durable clinical change. Standard, fixed‐amount DRO schedules have not commonly yielded such reductions, so we evaluated a novel, progressive‐amount DRO schedule, based on its ability to facilitate sustained abstinence from functionally similar behaviors. Five youth with CTDs were exposed to periods of baseline, fixed‐amount DRO (DRO‐F), and progressive‐amount DRO (DRO‐P). Both DRO schedules …

The International Deep Brain Stimulation Registry And Database For Gilles De La Tourette Syndrome: How Does It Work?, Wissam Deeb, Peter J. Rossi, Mauro Porta, Veerle Visser-Vandewalle, Domenico Servello, Peter Silburn, Terry Coyne, James F. Leckman, Thomas Foltynie, Marwan Hariz, Eileen M. Joyce, Ludvic Zrinzo, Zinovia Kefalopoulou, Marie-Laure Welter, Carine Karachi, Luc Mallet, Jean-Luc Houeto, Joohi Shahed-Jimenez, Fan-Gang Meng, Brian T. Klassen, Alan Y. Mogilner, Michael H. Pourfar, Jens Kuhn, L. Ackermans, Takanobu Kaido, Yasin Temel, Robert E. Gross, Harrison C. Walker, Andres M. Lozano, Suketu M. Khandhar, Benjamin L. Walter, Ellen Walter, Zoltan Mari, Barbara K. Changizi, Elena Moro, Juan C. Baldermann, Daniel Huys, S. Elizabeth Zauber, Lauren E. Schrock, Jian-Guo Zhang, Wei Hu, Kelly D. Foote, Kyle Rizer, Jonathan W. Mink, Douglas W. Woods, Aysegul Gunduz, Michael S. Okun

Psychology Faculty Research and Publications

Tourette Syndrome (TS) is a neuropsychiatric disease characterized by a combination of motor and vocal tics. Deep brain stimulation (DBS), already widely utilized for Parkinson's disease and other movement disorders, is an emerging therapy for select and severe cases of TS that are resistant to medication and behavioral therapy. Over the last two decades, DBS has been used experimentally to manage severe TS cases. The results of case reports and small case series have been variable but in general positive. The reported interventions have, however, been variable, and there remain non-standardized selection criteria, various brain targets, differences in hardware, as …

Pilot Testing Behavior Therapy For Chronic Tic Disorders In Neurology And Developmental Pediatrics Clinics, Emily J. Ricketts, Donald L. Gilbert, Samuel H. Zinner, Jonathan W. Mink, Tara D. Lipps, Geoffrey A. Wiegand, Amy E. Vierhile, Laura J. Ely, John Piacentini, John T. Walkup, Douglas W. Woods

Psychology Faculty Research and Publications

Comprehensive Behavioral Intervention for Tics (CBIT) is an efficacious treatment with limited regional availability. As neurology and pediatric clinics are often the first point of therapeutic contact for individuals with tics, the present study assessed preliminary treatment response, acceptability, and feasibility of an abbreviated version, modified for child neurology and developmental pediatrics clinics. Fourteen youth (9-17) with Tourette disorder across 2 child neurology clinics and one developmental pediatrics clinic participated in a small case series. Clinician-rated tic severity (Yale Global Tic Severity Scale) decreased from pre- to posttreatment, z = –2.0, P < .05, r = –.48, as did tic-related impairment, z …