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Full-Text Articles in Social and Behavioral Sciences
Taking The Perspective That A Depressive State Reflects Inflammation: Implications For The Use Of Antidepressants, Jill Littrell
Taking The Perspective That A Depressive State Reflects Inflammation: Implications For The Use Of Antidepressants, Jill Littrell
jill l littrell Dr.
This paper reviews both the evidence that supports the characterization of depression as an inflammatory disorder and the different biochemical mechanisms that have been postulated for the connection between inflammation and depression. This association offers credible explanation for the short term efficacy of antidepressants, which have short term anti-inflammatory effects. Evidence for those anti-inflammatory effects is discussed. Evidence of the contrary long-term effects of antidepressants, which increase rather than decrease inflammation, is also reviewed. It is argued that this increase in inflammation would predict an increase in chronicity among depressed patients that have been treated with antidepressants drugs, which has …
Effect Of Apolipoprotein Ε4 On Hippocampal And Brain Volume In Intractable Temporal Lobe Epilepsy, Robyn Busch, Darlene Floden, Tara Lineweaver, Jessica Chapin, Kanjana Ungwongse, Tim Wehner, Ramon Diaz-Arrastia, Imad Najm
Effect Of Apolipoprotein Ε4 On Hippocampal And Brain Volume In Intractable Temporal Lobe Epilepsy, Robyn Busch, Darlene Floden, Tara Lineweaver, Jessica Chapin, Kanjana Ungwongse, Tim Wehner, Ramon Diaz-Arrastia, Imad Najm
Tara T. Lineweaver
This study investigated the relationship between the apolipoprotein (APOE) ε4 allele and brain volumes in patients with medically intractable temporal lobe epilepsy (TLE). MRI-based volumetric analyses of the hippocampi, cerebral hemispheres, and whole brain were conducted in 59 patients with TLE (31 with left TLE, 28 with right TLE) with hippocampal sclerosis (HS). There were no differences in hippocampal, hemispheric, or whole brain volumes as a function of ε4 status even after correcting for hemispheric and total brain volumes. However, APOE ε4 carriers showed a trend toward having a smaller discrepancy between ipsilateral and contralateral hippocampal volumes than patients without …
In-Hospital Depression Predicts Early Hospital Readmission After An Acute Coronary Syndrome: Preliminary Data From Trace-Core, David Mcmanus, Jane Saczynski, Molly Waring, Milena Anatchkova, Richard Mcmanus, Robert Goldberg, Jeroan Allison, David Parish, Hamza Awad, Jerry Gurwitz, Arlene Ash, Catarina Kiefe
In-Hospital Depression Predicts Early Hospital Readmission After An Acute Coronary Syndrome: Preliminary Data From Trace-Core, David Mcmanus, Jane Saczynski, Molly Waring, Milena Anatchkova, Richard Mcmanus, Robert Goldberg, Jeroan Allison, David Parish, Hamza Awad, Jerry Gurwitz, Arlene Ash, Catarina Kiefe
Richard H. McManus
Background: Hospital systems, patients and providers seek to avert rehospitalizations within 30 days for patients admitted with an acute coronary syndrome (ACS). Rehospitalizations within 30 days of discharge are often considered preventable and to reflect poor in-hospital management or discharge practices. However, independent associations of psychosocial factors with early rehospitalization in patients admitted with an ACS have not been examined. Methods: A multi-racial cohort of 1,540 patients admitted with an ACS reported psychosocial factors via standardized questionnaires in an in-hospital interview. One month following discharge, patients were interviewed via phone and reported hospital readmissions. We used logistic regression models to …
An Introduction To Drugs And The Neuroscience Of Behavior, Adam Prus
An Introduction To Drugs And The Neuroscience Of Behavior, Adam Prus
Adam J Prus
This up-to-date new text provides an introductory overview of the nervous system actions and behavioral effects of the major classes of psychoactive drugs. Appropriate for undergraduate students who have an introductory level background in psychology or other areas within the social sciences, AN INTRODUCTION TO DRUGS AND THE NEUROSCIENCE OF BEHAVIOR illustrates concepts and highlights research techniques. The book's most important feature is its pedagogical elements, which are not found in other psychopharmacology texts, but are particularly important for making this specialized topic approachable for undergraduates. Charts and diagrams illustrate basic concepts and processes important for understanding the actions and …
Predictors Of Posttraumatic Stress Disorder, Depression, And Suicidal Ideation Among Canadian Forces Personnel In A National Canadian Military Health Survey, Charles Nelson, Kate St. Cyr, Bradley Corbett, Elisa Hurley, Shannon Gifford, Jon Elhaid, J. Richardson
Predictors Of Posttraumatic Stress Disorder, Depression, And Suicidal Ideation Among Canadian Forces Personnel In A National Canadian Military Health Survey, Charles Nelson, Kate St. Cyr, Bradley Corbett, Elisa Hurley, Shannon Gifford, Jon Elhaid, J. Richardson
Bradley Corbett
Despite efforts to elucidate the relationship between traumatic event exposure and adverse mental health outcomes, our ability to understand why only some trauma-exposed individuals become emotionally affected remains challenged. The aim of the current study is to determine the relations between social support, religiosity, and number of lifetime traumatic events experienced on past-12 month posttraumatic stress disorder (PTSD), depression, and suicidal ideation (SI) in a nationally representative sample of Canadian Forces personnel. The current study used data from the Canadian Community Health Survey Cycle 1.2 – Canadian Forces Supplement. The impact of a number of predictive and mediating factors was …