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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
A Novel Approach For Classifying Gene Expression Data Using Topic Modeling, Soon Jye Kho, Himi Yalamanchili, Michael L. Raymer, Amit Sheth
A Novel Approach For Classifying Gene Expression Data Using Topic Modeling, Soon Jye Kho, Himi Yalamanchili, Michael L. Raymer, Amit Sheth
Kno.e.sis Publications
Understanding the role of differential gene expression in cancer etiology and cellular process is a complex problem that continues to pose a challenge due to sheer number of genes and inter-related biological processes involved. In this paper, we employ an unsupervised topic model, Latent Dirichlet Allocation (LDA) to mitigate overfitting of high-dimensionality gene expression data and to facilitate understanding of the associated pathways. LDA has been recently applied for clustering and exploring genomic data but not for classification and prediction. Here, we proposed to use LDA inclustering as well as in classification of cancer and healthy tissues using lung cancer …
Making Use Of The Most Expressive Jumping Emerging Patterns For Classification, Jinyan Li, Guozhu Dong, Kotagiri Ramamohanarao
Making Use Of The Most Expressive Jumping Emerging Patterns For Classification, Jinyan Li, Guozhu Dong, Kotagiri Ramamohanarao
Kno.e.sis Publications
Classification aims to discover a model from training data that can be used to predict the class of test instances. In this paper, we propose the use of jumping emerging patterns (JEPs) as the basis for a new classifier called the JEP-Classifier. Each JEP can capture some crucial difference between a pair of datasets. Then, aggregating all JEPs of large supports can produce a more potent classification power. Procedurally, the JEP-Classifier learns the pair-wise features (sets of JEPs) contained in the training data, and uses the collective impacts contributed by the most expressive pair-wise features to determine the class labels …