Social and Behavioral Sciences Commons^™

The Common Ovine Shiga Toxin 2-Containing Escherichia Coli Serotypes And Human Isolates Of The Same Serotypes Possess A Stx2d Toxin Type, Vidiya Ramachandran, Michael A. Hornitzky, Karl A. Bettelheim, Mark J. Walker, Steven P. Djordjevic

Faculty of Science, Medicine and Health - Papers: part A

Shiga toxin 2 (Stx2) has been reported as the main Shiga toxin associated with human disease. In addition, the Stx2 toxin type can have a profound impact on the degree of tissue damage in animal models. We have characterized the stx₂ subtype of 168 Shiga toxin-producing Escherichia coli (STEC) isolates of which 146 were derived from ovine sources (principally feces and meat) and 22 were isolated from humans. The ovine STEC isolates were of serotypes that have been shown to occur commonly in the gastrointestinal tract of healthy sheep. The major stx₂ subtype in the ovine isolates was …