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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Aged Rats: Sex Differences And Responses To Chronic Stress, Rachel E. Bowman, Neil J. Maclusky, Samantha Diaz-Weinstein, Mark C. Zrull, Victoria N. Luine
Aged Rats: Sex Differences And Responses To Chronic Stress, Rachel E. Bowman, Neil J. Maclusky, Samantha Diaz-Weinstein, Mark C. Zrull, Victoria N. Luine
Psychology Faculty Publications
Cognitive, as well as physiological, sex differences exist in young adult rats under both basal conditions and following chronic stress; however, few studies have examined whether sex differences remain in aged subjects and whether responses to stress are altered. We compared aged male and female Fischer 344 rats (21.5 months at testing) without stress and when given 21 days of restraint for 6 h/day on locomotion, anxiety-related behaviors, object recognition (non-spatial memory), object placement (spatial memory), body weight and serum steroid hormone levels. Control (unstressed) females had lower levels of estradiol and testosterone and higher corticosterone than males, and stress …
Limbic Hyperactivation During Processing Of Neutral Facial Expressions In Children With Bipolar Disorder, Brendan A. Rich, Deborah T. Vinton, Roxann Roberson-Nay, Lisa H. Berghorst, Erin B. Mcclure, Stephen Fromm, Daniel Pine, Ellen Leibenluft
Limbic Hyperactivation During Processing Of Neutral Facial Expressions In Children With Bipolar Disorder, Brendan A. Rich, Deborah T. Vinton, Roxann Roberson-Nay, Lisa H. Berghorst, Erin B. Mcclure, Stephen Fromm, Daniel Pine, Ellen Leibenluft
Psychology Faculty Publications
A major paradigm shift in mental health has led to the ascendance of the view that chronic psychopathology results from perturbed neural development. While most work in this area examines schizophrenia, the current report extends the paradigm to bipolar disorder (BD) in youth, thus demonstrating traction (not sure I understand what you mean here) in the developmental-psychobiology perspective. To study the role of amygdala dysfunction, we examined the neural mechanisms mediating face processing in 22 youth (mean age 14.21 + 3.11 years) with BD and 21 controls of comparable age, gender, and IQ. Event-related fMRI compared neural activation when attention …