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Social and Behavioral Sciences Commons

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Full-Text Articles in Social and Behavioral Sciences

Long-Term Effects Of Adolescent Fluoxetine Exposure On Hippocampal Gene Expression In Male C57bl/6 Mice, Anapaula Themann Dec 2021

Long-Term Effects Of Adolescent Fluoxetine Exposure On Hippocampal Gene Expression In Male C57bl/6 Mice, Anapaula Themann

Open Access Theses & Dissertations

Mood-related disorders, including depression and anxiety, are prevalent among children and adolescents. This poses a public health challenge, given their adverse impact on these young populations. Treatment with the selective serotonin reuptake inhibitor fluoxetine (FLX) is the first line of pharmacological intervention in pediatric patients suffering from affect-related illnesses. Although the use of this antidepressant has been deemed efficacious in the juvenile population, the enduring neurobiological consequences of adolescent FLX exposure are not well understood. For this reason, we explored for persistent molecular adaptations, in the adult hippocampus, as a function of adolescent FLX pretreatment. To do this, we administered …


Transgenerational Differences Between Two Culturally Distinct Prairie Vole Populations, Richard Joaquin Ortiz Dec 2021

Transgenerational Differences Between Two Culturally Distinct Prairie Vole Populations, Richard Joaquin Ortiz

Open Access Theses & Dissertations

Culture can be described as a system of environmental beliefs, values, and social practices within one’s environment. This system is passed on from generation to generation and provides a basis for an individual’s behaviors and cognitive perceptions. Cultural neuroscience is an emerging field that intertwines domains of anthropology, psychology, neuroscience, and genetics to help understand the underlying processes, neural mechanisms and genomic factors that vary across cultures. Similar to humans, the socially monogamous prairie vole (Microtus ochrogaster) display populational differences in prosocial behavior and aggression based upon region-specific cultural upbringing and parental lineage. Prairie voles originating from Kansas (KS) display …


Effects Of Repeated Nicotine Vapor Exposure And Withdrawal On Somatic Signs, Anxiety-Like Behavior, And Brain Reward Thresholds In Male Sprague Dawley Rats, Michelle Martinez May 2021

Effects Of Repeated Nicotine Vapor Exposure And Withdrawal On Somatic Signs, Anxiety-Like Behavior, And Brain Reward Thresholds In Male Sprague Dawley Rats, Michelle Martinez

Open Access Theses & Dissertations

No abstract provided.