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- Keyword
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- ADCC (1)
- Abdominal aortic aneurysm; primary prevention; atherosclerosis; smoking; dyslipidemia. (1)
- COVID-19 (1)
- ChemoID; head & neck cancer; oral cancer; oral squamous cell carcinoma; chemotherapy; individualized therapy; personalized medicine. (1)
- Conflict of Interest; Evidence-Based Medicine; Allergen-specific Immunotherapy; Randomized controlled trials; Meta-analysis; Systematic review. (1)
Articles 1 - 7 of 7
Full-Text Articles in Social and Behavioral Sciences
The Role Of The Nurse In The Management Of Irritable Bowel Syndrome: A Narrative Review, Luigi Ruggiero, Vincenzo Andretta, Carlo Soldaini, Ivan Fricano, Marco Mancusi, Annamaria Sellitti, Josephine Vastarella, Antonella Santonicola
The Role Of The Nurse In The Management Of Irritable Bowel Syndrome: A Narrative Review, Luigi Ruggiero, Vincenzo Andretta, Carlo Soldaini, Ivan Fricano, Marco Mancusi, Annamaria Sellitti, Josephine Vastarella, Antonella Santonicola
Translational Medicine @ UniSa
rritable bowel syndrome (IBS) is characterized by chronic symptoms of abdominal pain in association with changes in bowel habits. Abdominal pain is the most debilitating symptom for IBS patients, and its management is one of the greatest challenges for gastroenterologists. In recent years more evidence has arisen about an increasingly central role of the nurse in the management of gastrointestinal diseases including IBS. The aim of this narrative review is to analyse the latest evidence on the pathophysiology, diagnosis, and treatment of IBS patients with a specific focus on the role of the nurse in its management.
A New And Effective Procedure For Advanced Oral Cancer Therapy: The Potential Of A Cancer Stem Cell Assay In Guiding Chemotherapy, Francesca Spirito, Pier Paolo Claudio, Candace M. Howard, Jagan Valluri, Krista L. Denning, Lorenzo Lo Muzio, Antonio Cortese
A New And Effective Procedure For Advanced Oral Cancer Therapy: The Potential Of A Cancer Stem Cell Assay In Guiding Chemotherapy, Francesca Spirito, Pier Paolo Claudio, Candace M. Howard, Jagan Valluri, Krista L. Denning, Lorenzo Lo Muzio, Antonio Cortese
Translational Medicine @ UniSa
Introduction Ineffective anticancer therapy can result in unnecessary toxicity and the development of resistant clones. Many types of solid tumors, including head and neck squamous cell carcinoma, have been found to contain a small population of cancer stem cells (CSCs) that contribute to tumor propagation, maintenance, and treatment resistance. Materials and Methods Selectively enriched CSCs from primary cancer cell cultures can be used in a chemosensitivity assay for a functional test (ChemoID) that uses patients’ live tumor cells to indicate which chemotherapy agent (or “combinations”) will kill not only the bulk of tumor cells but also the CSCs that are …
Sicilian Semi- And Supercentenarians: Age-Related Nk Cell Immunophenotype And Longevity Trait Definition, Mattia Emanuela Ligotti, Giulia Accardi, Anna Aiello, Anna Calabrò, Calogero Caruso, Anna Maria Corsale, Francesco Dieli, Marta Di Simone, Serena Meraviglia, Giuseppina Candore
Sicilian Semi- And Supercentenarians: Age-Related Nk Cell Immunophenotype And Longevity Trait Definition, Mattia Emanuela Ligotti, Giulia Accardi, Anna Aiello, Anna Calabrò, Calogero Caruso, Anna Maria Corsale, Francesco Dieli, Marta Di Simone, Serena Meraviglia, Giuseppina Candore
Translational Medicine @ UniSa
The immune system of semi- and super-centenarians (i.e., the oldest centenarians) is believed to have peculiar characteristics that enable them to reach extreme longevity in a relatively healthy state. Therefore, in previous papers, we investigated, through flow cytometry, variations in the percentages of the main subsets of Tαβ and Tγδ cells in a Sicilian cohort of 28 women and 26 men (age range 19-110 years), including 11 long-living individuals (>90 years old) and 8 oldest centenarians. These investigations suggested that some observed immunophenotypic changes may contribute to the extreme longevity of the oldest centenarians. In the present study, to …
What Evidence-Based Medicine (Ebm) Doesn't Say About Allergen-Specific Immunotherapy (Ait), Gabriele Di Lorenzo, Marcello Melluso, Alessandro Rodolico
What Evidence-Based Medicine (Ebm) Doesn't Say About Allergen-Specific Immunotherapy (Ait), Gabriele Di Lorenzo, Marcello Melluso, Alessandro Rodolico
Translational Medicine @ UniSa
Evidence-based allergology for the treatment of allergic rhinitis with allergen-specific immunotherapy (AIT) has been used in publications by the companies manufacturing AIT. The purpose of randomized controlled trials (RCTs) is to provide physicians, health authorities, patients, and their families with the best evidence upon which to base treatment decisions. However, some RCT results may do more harm than good because they serve the commercial interests of the companies producing and marketing AIT more than the interests of patients. Allergic rhinitis is a trivial disease that is not life-threatening and is easily controlled by drugs. In this paper, we analyze some …
Abdominal Aortic Aneurysm: Natural History, Pathophysiology And Translational Perspectives, Giulio Accarino, Antonio Nicola Giordano, Martina Falcone, Adriana Celano, Maria Giovanna Vassallo, Giovanni Fornino, Umberto Marcello Bracale, Carmine Vecchione, Gennaro Galasso
Abdominal Aortic Aneurysm: Natural History, Pathophysiology And Translational Perspectives, Giulio Accarino, Antonio Nicola Giordano, Martina Falcone, Adriana Celano, Maria Giovanna Vassallo, Giovanni Fornino, Umberto Marcello Bracale, Carmine Vecchione, Gennaro Galasso
Translational Medicine @ UniSa
An abdominal aortic aneurysm (AAA) is a degenerative pathology that affects the infrarenal segment of the aorta, leading to its progressive dilatation and eventually rupture. The infrarenal segment is involved in 80% of the aortic aneurisms, and represents alone 30% of all aneurysms. The natural history of the disease is characterized by the progressive increase of the aortic diameter associated with proportionally higher risk of rupture, particularly for cases with diameter greater than 5.5 cm. In case of rupture the mortality rate is very high, independently from the endovascular or surgical treatment. The most important risk factors are older age, …
Gm Allotypes And Covid-19. A Pilot Study Performed On Sicilian Patients, Mattia Emanuela Ligotti, Anna Calabrò, Giulia Accardi, Anna Aiello, Calogero Caruso, Claudia Colomba, Danilo Di Bona, Giovanni Duro, Aryan M Namboodiri, Antonino Tuttolomondo, Janardan P Pandey, Giuseppina Candore
Gm Allotypes And Covid-19. A Pilot Study Performed On Sicilian Patients, Mattia Emanuela Ligotti, Anna Calabrò, Giulia Accardi, Anna Aiello, Calogero Caruso, Claudia Colomba, Danilo Di Bona, Giovanni Duro, Aryan M Namboodiri, Antonino Tuttolomondo, Janardan P Pandey, Giuseppina Candore
Translational Medicine @ UniSa
Several studies suggest that genetic variants that influence the onset, maintenance and resolution of the immune response might be fundamental in predicting the evolution of COVID-19. In the present paper, we analysed the distribution of GM allotypes (the genetic markers of immunoglobulin γ chains) in symptomatic and asymptomatic COVID-19 patients and in healthy controls, all born and residing in Sicily. Indeed, the role played by GM allotypes in immune responses and infection control is well known. Our findings show that the GM23 allotype is significantly reduced in healthy controls. Interestingly, in a previous study, Sicilians carrying the GM23 allotype were …
Translating The Results Of A Selective Decontamination Of The Digestive Tract Trial Into Efficacious Real-Life Interventions, Ornella Piazza, Giovanni Boccia, Carolina Ciacci, Francesco De Caro, Amelia Filippelli, Gianluigi Franci, Pasquale Pagliano
Translating The Results Of A Selective Decontamination Of The Digestive Tract Trial Into Efficacious Real-Life Interventions, Ornella Piazza, Giovanni Boccia, Carolina Ciacci, Francesco De Caro, Amelia Filippelli, Gianluigi Franci, Pasquale Pagliano
Translational Medicine @ UniSa
No Abstract for this article type.