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Social and Behavioral Sciences Commons

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Full-Text Articles in Social and Behavioral Sciences

Sport And Mental Health Performance Optimization In An Adolescent Gymnast: A Case Evaluation, Davy Phrathep, Brad C. Donohue, Brenna N. Renn, John Mercer Dr., Daniel N. Allen Feb 2023

Sport And Mental Health Performance Optimization In An Adolescent Gymnast: A Case Evaluation, Davy Phrathep, Brad C. Donohue, Brenna N. Renn, John Mercer Dr., Daniel N. Allen

Psychology Faculty Research

The Optimum Performance Program in Sports (TOPPS) is a multi-component, sport-specific Family Behavior Therapy that has demonstrated improved sport performance, relationships, and mental health outcomes in adult and adolescent athletes with, and without, diagnosed mental health disorders in clinical trials. The current case trial demonstrates successful implementation of a novel component of TOPPS (i.e., talk aloud optimal sport performance imagery leading to dream mapping) in a biracial Latina and White adolescent gymnast without a mental health diagnosis. The participant demonstrated significant improvements from baseline to both post-treatment and 3-month follow-up in severity of mental health functioning, factors interfering with sports …


Identification Of A Core Amino Acid Motif Within The Α Subunit Of Gabaars That Promotes Inhibitory Synaptogenesis And Resilience To Seizures, Anna J. Nathanson, Yihui Zhang, Joshua L. Smalley, Thomas A. Ollerhead, Miguel A. Rodriguez Santos, Peter M. Andrews, Heike J. Wobst, Yvonne E. Moore, Nicholas J. Brandon, Rochelle M. Hines, Paul A. Davies, Stephen J. Moss Jul 2019

Identification Of A Core Amino Acid Motif Within The Α Subunit Of Gabaars That Promotes Inhibitory Synaptogenesis And Resilience To Seizures, Anna J. Nathanson, Yihui Zhang, Joshua L. Smalley, Thomas A. Ollerhead, Miguel A. Rodriguez Santos, Peter M. Andrews, Heike J. Wobst, Yvonne E. Moore, Nicholas J. Brandon, Rochelle M. Hines, Paul A. Davies, Stephen J. Moss

Psychology Faculty Research

The fidelity of inhibitory neurotransmission is dependent on the accumulation of γ-aminobutyric acid type A receptors (GABAARs) at the appropriate synaptic sites. Synaptic GABAARs are constructed from α(1-3), β(1-3), and γ2 subunits, and neurons can target these subtypes to specific synapses. Here, we identify a 15-amino acid inhibitory synapse targeting motif (ISTM) within the α2 subunit that promotes the association between GABAARs and the inhibitory scaffold proteins collybistin and gephyrin. Using mice in which the ISTM has been introduced into the α1 subunit (Gabra1-2 mice), we show that the ISTM is critical for axo-axonic synapse formation, the efficacy of GABAergic …