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Full-Text Articles in Social and Behavioral Sciences
Cumulative Neurological Factors Associated With Long-Term Outcomes In Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Sabrina Na
Cumulative Neurological Factors Associated With Long-Term Outcomes In Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Sabrina Na
Psychology Faculty Publications
Prior research has demonstrated the reliability and validity of the Neurological Predictor Scale (NPS) in relation to childhood brain tumor survivor outcomes; however, its use has not been examined in adult long-term survivors. The current study examines the concurrent validity of the NPS with long-term intellectual and adaptive outcomes in adult survivors of childhood brain tumors relative to individual variables alone. A total of 68 adult survivors of childhood brain tumors (M = 24 years old, SD = 4) almost 16 years post diagnosis (SD = 6) completed intellectual evaluations using the Wechsler Abbreviated Scale of Intelligence (WASI). Survivors' adaptive …
The Mediating Role Of Visuospatial Planning Skills On Adaptive Function Among Young Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Kristin M. Smith, Mirjana Ivanisevic
The Mediating Role Of Visuospatial Planning Skills On Adaptive Function Among Young Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Kristin M. Smith, Mirjana Ivanisevic
Psychology Faculty Publications
The Boston Qualitative Scoring System (BQSS) was used as a method to examine executive skills on the Rey-Osterrieth complex figure (ROCF). Young adult survivors of childhood brain tumor (N = 31) and a demographically-matched comparison group (N = 33) completed the ROCF copy version and Grooved Pegboard, and informants were administered the Scales of Independent Behavior-Revised (SIB-R) and Behavior Rating Inventory of Executive Function (BRIEF). Survivors had significantly lower BQSS planning and SIB-R community living skills and greater perseveration. Mediation analyses found that BQSS planning skills mediate the relationship between group and community living skills. Convergent findings of the BRIEF …
Hippocampal Volume And Auditory Attention On A Verbal Memory Task With Adult Survivors Of Pediatric Brain Tumor, Reema Jayakar, Tricia Z. King, Robin Morris, Sabrina Na
Hippocampal Volume And Auditory Attention On A Verbal Memory Task With Adult Survivors Of Pediatric Brain Tumor, Reema Jayakar, Tricia Z. King, Robin Morris, Sabrina Na
Psychology Faculty Publications
Objective: We examined the nature of verbal memory deficits and the possible hippocampal underpinnings in long-term adult survivors of childhood brain tumor. Method: 35 survivors (M=24.10±4.93 years at testing; 54% female), on average 15 years post-diagnosis, and 59 typically developing adults (M=22.40±4.35 years, 54% female) participated. Automated FMRIB Software Library (FSL) tools were used to measure hippocampal, putamen, and whole brain volumes. The California Verbal Learning Test – Second Edition (CVLT-II) was used to assess verbal memory. Results: Hippocampal (F(1,91)=4.06, ηp2=.04), putamen (F(1,91)=11.18, ηp2=.11), and whole brain (F(1,92)=18.51, …
Neural Underpinnings Of Working Memory In Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Sabrina Na, Hui Mao
Neural Underpinnings Of Working Memory In Adult Survivors Of Childhood Brain Tumors, Tricia Z. King, Sabrina Na, Hui Mao
Psychology Faculty Publications
Objective: Adult survivors of childhood brain tumors are at risk for cognitive performance deficits that require the core cognitive skill of working memory. Our goal was to examine the neural mechanisms underlying working memory performance in survivors. Method: We studied the working memory of adult survivors of pediatric posterior fossa brain tumors using a letter n-back paradigm with varying cognitive workload (0-, 1-, 2-, and 3-back) and functional magnetic resonance imaging as well as neuropsychological measures. Results: Survivors of childhood brain tumors evidenced lower working memory performance than demographically-matched healthy controls. Whole-brain analyses revealed significantly greater blood-oxygen level dependent (BOLD) …