Social and Behavioral Sciences Commons^™

Effects Of Mercury On The Dopamine Transporter Cell Surface Expression In Pc12 Cells, Christina Hui

Student Theses

Environmental factors, such as heavy metal exposures, have been suggested to have an impact not only on neurodegenerative disease, such as Parkinson’s disease, but also on psychostimulants abuse and their toxicity. In this study, two questions were addressed: 1) effects of mercuric chloride on parkinsonian toxicant 1-methyl-4-phenylpyridinium (MPP⁺) induced cytotoxicity and 2) effects of mercuric chloride on cell surface dopamine transporter. Pheochromocytorma cells (PC12) were treated with various concentrations of mercuric chloride (0.02~2.0 ppm) for 4 hours with and without 0.1 mM MPP⁺. Significant potentiation of toxicity was observed when there was co-treatment with 0.5 ppm …

Evaluation Of A Novel Dna Collection Matrix Designed To Improve Recovery Of Touch Dna From Non-Porous Surfaces, Eric Ramirez

Student Theses

The collection of touch DNA from evidence has been a challenge in the field of Forensic Biology for decades. There are numerous collection protocols, substrates, and solutions that have been used to varying levels of success. Currently, no single method or substrate stands out as the single most effective collection protocol. The Gene Link Omni Matrix™ K105 solution is a novel collection method that can be sprayed onto the surface of non-porous evidence. The matrix dries into a film, capturing cells and cell-free DNA which can be scraped off and collected into a tube. During extraction, the matrix dissolves into …

Dna Mixture Statistics Using A Likelihood Ratio Software Tool: Effect Of Variations In Drop-Out Rates And Number Of Contributors, Felicia M. Lucero

Student Theses

Complex DNA mixtures can be very probative evidence, but comparisons to a person of interest can be affected by allelic drop-out and uncertainty regarding the number of individuals having contributed DNA to a sample. Scientific organizations such as the International Society of Forensic Genetics (Gill et al., 2006) recommend that likelihood ratios should be used to provide a statistical weight when a positive association is made between the DNA profile of a person of interest and an evidentiary DNA sample. To this effect the New York City Office of Chief Medical Examiner (OCME) developed a software program, Forensic Statistical Tool …

The Feedback Effect: Does Exposure To Interviewer Feedback Affect An Observer's Perception Of Veracity And Guilt?, Kayla A. Harrod

Student Theses

Historically, assessing deception has been rooted in the belief that a guilty suspect displays signs of anxiety. Based on a suspect’s physical demeanor and other behavioral cues presented during an interrogative session, law enforcement personnel (LEP) will utilize a set of techniques to elicit information about a crime. One such technique is the administration of feedback, which is the verbal assessment of a suspect’s guilt. The issue that stems from administering feedback lies not only in how it is given but also how it is received and interpreted by others. In a two-part study, the possibility of a “Feedback Effect” …

A Microspectra Analysis Of Synthetic Wig Fibers, Jaclyn R. Beshlian

Student Theses

The goal of this study was to determine whether differentiation between 20 visually similar light brown synthetic wig fibers was possible with the use of a microspectrophotometer (MSP). Visually similar fibers were chosen to display the power of the instrument over the human eye. An MSP is an instrument that has the ability to aid in the analysis of certain microscopical samples. With this particular instrument one is able to collect the absorption and fluorescence spectra of microscopical colored samples without destroying the piece of evidence itself. Prior to any analysis with the MSP, the material of the fibers was …

Dna Recovery From Handwritten Documents Using A Novel Vacuum Technique, Patrick M. Mclaughlin

Student Theses

Investigations of many crimes such as robberies, kidnappings, and terrorism are often associated with the recovery of a paper document which has been written by the perpetrator. Paper can provide a variety of forensic evidence such as DNA, latent fingermarks, and indented writing. The focus of this study was the collection of probative DNA profiles from the text region of a handwritten note through a vacuum suction device without altering or destroying the document. Collection of DNA evidence was carried out in two separate groups. The first group involved 11 volunteers providing a handwritten note sample with unwashed hands. The …

An Exploration Of Protein And Dna Components In Fingerprint Residue, Ashley Borrego

Student Theses

The main focus of this project was to investigate the protein and DNA components in both sebaceous and eccrine fingerprints. This study investigated the relative content of DNA and proteins in eccrine fingerprints to sebaceous fingerprints. All volunteers were instructed to wash and dry their hands prior to depositing parallel thumbprints. Twenty volunteers were instructed to touch their face to produce sebaceous prints, and 5 volunteers were instructed to wear gloves over a heat source to produce sweaty or eccrine prints. Microscopy was used to score the cellular debris of the right fingerprint on a scale of 1-4 based on …

The Role Of Eyewitness Confidence And Prosecution/Defense Presentation In How Facial Composites Shape Juror Decision-Making, Rebecca E. Singh

Student Theses

Eyewitness testimony has been found to be an unreliable form of evidence (Loftus, Miller & Burns, 1978; Oswald & Coleman, 2007; Wells & Hasel, 2007; Loftus & Greenspan, 2017; Jaross, 2018; Wade, Nash, & Lindsay, 2018; Wixted, Mickes, & Fisher, 2018). Yet, this evidence is still used in the courts today, and, in fact, is perceived by jurors as important and compelling in comparison to other case factors (e.g., character evidence, physical evidence; Topp-Manriquez, McQuiston, & Malpass, 2014; Kabzińska, 2015). Additionally, eyewitnesses are sometimes requested to help create a facial composite of the suspect and, critically, these composites are then …

The Impact Of Client's Gender And Culture On Service Providers Strategies In Diversion Programs, Stephany Betances

Student Theses

Despite the growing rate of adolescent girls in the criminal justice system, there has been little institutional support for empirically supported programs tailored for girls (Matthews & Hubbard, 2008). There is a similar substantial lack of culturally specific programming. Problematically, both constructs have been found to impact treatment (Bright & Jonson-Reid, 2010; Matthews & Hubbard, 2008). This qualitative study utilized grounded theory principals to investigate the impact of gender and culture on the therapeutic relationship for justice-involved youth in seven alternative-to-incarceration agencies in New York City. Elicited themes focused on both recommended strategies and continued challenges. Results indicated that while …

Method Development And Validation For The Determination Of Designer Benzodiazepines In Blood By Lc-Ms/Ms, Victoria Mei

Student Theses

The misuse of designer benzodiazepines, as an alternative to prescription benzodiazepines and for drug-facilitated sexual assaults, has emerged as a growing threat, due in part to the ease of purchasing these drugs on the internet at low prices. Causing concern for safety, is the lack of dosage information resulting in users self-medicating, often leading to unintended overdoses, coma, or death at higher doses. With limited published data regarding quantification of designer benzodiazepines in forensic cases, a method was validated for the determination of thirteen and screening for two designer benzodiazepines in blood, in addition to a limited number of common …

Gender Based Violence In India: An Analysis Of National Level Data For Theory, Research And Prevention, Dhanya Babu

Student Theses

Gender based violence is a human rights violation, both the causes and impacts of which crosses personal, societal and cultural boundaries. Various initiatives to address the problem of gender-based violence have resulted in many countries attempting to quantify the extent of such crimes. The purpose of this present study is to examine nature and extent of GBV in India for prevention policy actions. The National Crime Record Bureau (NCRB) of India publishes a consolidated list of reported crime happenings in the country every year. Recognizing gendered aspect of certain crimes, the NCRB maintains a separate chapter on incidences of crimes …

The Forensic Analysis Of Children's Temporary Tattoos, Erika Bravo

Student Theses

While children’s temporary tattoos have been produced since the 20th century, there are few scientific studies that have evaluated their physical and chemical characteristics. Therefore, this thesis is a preliminary study done to evaluate the composition of children’s temporary tattoos and consider the importance of such traces in a forensic content.

Colored regions in children’s temporary tattoos, such as red, pink, yellow and orange, were found to fluoresce with the use of an alternative light source while the use of microscopy led to the identification of different printing patterns between temporary tattoos. However, limitations in the ability to determine the …

Linguistic Features Of False Confessions And Confessions Not In Dispute: A Corpus Analysis, Lucrezia Rizzelli

Student Theses

Confessions are considered the gold standard of evidence, and yet many cases of false confessions causing wrongful convictions have come to the surface in the past decades. Currently, a method to identify false confessions does not exist and studies focusing on the content of the confessions have found similarities rather than points of distinction. In this study, we approached confessions from a stylistic rather than qualitative point of view, utilizing corpus analysis to outline the linguistic features of two samples of confessions: false confessions (n=37) and confessions not in dispute (n=98). Subsequently, we created a model …

The Forensic Analysis Of Adult Temporary Tattoos, Paige Cooper

Student Theses

Adult temporary tattoos have become more popular, yet there is very little research on them, especially regarding their use in forensics. This poses a problem because forensic investigators may not be able to distinguish a temporary tattoo from a real tattoo, possibly hindering their investigation. In this study, various types of adult temporary tattoos were examined and analyzed in attempts to identify and distinguish them, both from each other and from permanent tattoos. Infrared spectroscopy, specifically attenuated total reflection (ATR), proved to be more useful than ultra-violet visible light spectroscopy in terms of analyzing the samples. The natural adult temporary …

Quorum Blockchain Stress Evaluation In Different Environments, Daniel P. Mera

Student Theses

In today’s world, the Blockchain technology is used for different purposes has brought an increment in the development of different Blockchain platforms, services, and utilities for storing data securely and efficiently. Quorum Blockchain, an Ethereum fork created by JPMorgan Chase, has placed itself in one of the widely used, efficient and trustful Blockchain platforms available today. Because of the importance which Quorum is contributing to the world, it is important to test and measure different aspects of the platform, not only to prove how efficient the software can be but as well as to have a clear view on what …

Stop, Question, And Frisk: A Tool Of Racial Control In New York City, Justice D. Evans

Student Theses

Broken Windows policing through the utilization of Stop, Question, and Frisk has been widely used by the New York City Police Department (NYPD) since the 1990s, as guaranteed by landmark Supreme Court Case Terry v. Ohio (1968). As a result, hundreds of minority citizens have been the victim of routine stops for minor offenses through this aggressive police tactic. This study utilizes 2017 NYPD Stop, Question, and Frisk Data to determine whether broken windows policing, through stop, question, and frisk, operates as a mode of racial control for African Americans in New York City. Through the utilization of chi-square analyses, …

Simultaneous Determination Of Fourteen Antipsychotic Drugs In Whole Blood By Solid Phase Extraction And Liquid Chromatography Tandem Mass Spectrometry, Theresa M. Dawe

Student Theses

Anti-psychotic drugs are commonly prescribed to patients to treat several mental conditions, such as bipolar, schizophrenia, and manic-depressive disorder. The analysis of anti-psychotic drugs in blood is a common practice in clinical and forensic toxicology, to monitor drug treatment (therapeutic drug monitoring) or to explain the cause of the impairment or intoxication in human performance and in postmortem cases. However, most of the current studies have been performed in plasma, and a limited number in blood. We developed and validated a method to confirm and quantify a panel of commonly prescribed anti-psychotic drugs in whole blood using solid phase extraction …

Fight, Flight, And Free Will: How Knowledge Of Biopsychosocial Effects Of Trauma Influence Free Will Beliefs And Punishment For Juvenile And Adult Offenders, Rachel Lazar

Student Theses

Justifications for punishment are generally grounded in retribution or consequentialism. Retribution presupposes a belief in free will, claiming that offenders freely and rationally choose to commit a criminal act, and are therefore deserving of punishment. Consequentialism does not necessitate a reliance on free will, and views punishment as means to a valuable end. In recent years, neuroscientific research has challenged the notion of free will, providing one pathway for a public shift away from retribution and towards consequentialism. However, methods by which to instill this doubt in laypeople are still being discovered. To date, no studies have attempted to instill …

Developing And Validating A Fast And Accurate Method To Quantify 18 Antidepressants In Oral Fluid Samples Using Spe And Lc-Msms, Sanghee S. Shin

Student Theses

Antidepressant drugs are one of the most widely used medicines for treating major depressive disorders for long time periods. Oral fluid (OF) testing offers an easy and noninvasive sample collection. Detection of antidepressants in OF is important in clinical and forensic settings, such as therapeutic drug monitoring and roadside testing for driving under influence. We developed and validated a comprehensive liquid chromatography tandem mass spectrometry method for 18 antidepressants (amitriptyline, bupropion, citalopram, clomipramine, cyclobenzaprine, desipramine, desvenlafaxine, doxepin, duloxetine, fluoxetine, imipramine, mirtazapine, nortriptyline, paroxetine, sertraline, trazodone, trimipramine, venlafaxine) in oral fluid collected by Quantisal® oral collection devices. 0.5 mL of Quantisal® …

Examining Witness Testimony In Domestic Homicides, Hana Chae

Student Theses

The present study investigated the effects of varying witness testimony on mock jurors’ perceptions of a case where a woman utilizes self-defense as a reason for killing her husband during a domestic dispute. A 3 (expert witness) x 3 (child witness) design was used to examine the effects of two different forms of expert testimony (Battered Woman Syndrome [BWS] & Social Agency [SA]) and its interaction with presence of child witness [age 5 & age 8]. Jury eligible participants (N = 245) were recruited from Amazon Mechanical Turk (MTurk). It was hypothesized that the presence of an expert witness would …

Lethal Use Of Force: Insights Into Mental Illness, Robert A. Ryan

Student Theses

Fatal use of force incidents involving police officers in the United States have recently seen widespread media attention, emotionally charged rhetoric, and calls for reform. The present study examines police use of force encounters with the mentally ill given the significant proportion of incidents and wanting body of literature. The objective of this study is to examine fatal police interactions to test whether those displaying signs of mental illness in encounters with law enforcement are more dangerous than those not displaying signs of mental illness. Open source data from the Washington Post were used from 2015 to 2018 (n=3942) due …

The Forensic Analysis Of Skin-Safe Stamp Pad Inks, Swetha Rajagopal

Student Theses

Skin-safe stamp pad inks are currently being used at locations such as clubs, zoos and other events with the purpose of stamping individuals that visit the location. This is done in an attempt to monitor the number and activity of visitors. Ink manufacturing companies generally tend to experiment with a number of different combinations of the different components of ink, in order to obtain desirable properties. The combinations are usually proprietary and that very nature of the inks ends up making them, possibly unique and individual. The analysis, identification and possible individualization of the chemical composition of these inks could …