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Full-Text Articles in Social and Behavioral Sciences
Evaluation Of The Age Of Evidence In Mock Biological Touch Evidence Samples, Emma P. Hirst
Evaluation Of The Age Of Evidence In Mock Biological Touch Evidence Samples, Emma P. Hirst
Master of Science in Forensic Science Directed Research Projects
As more sensitive DNA profiling techniques have been developed, questions about how and when the DNA was deposited have become a driving issue in forensic casework. Image flow cytometry (IFC) offers a way to estimate the time since deposition (TSD) of trace DNA samples based on individual cells' morphological and autofluorescence properties. Previous work has shown that a TSD can be determined from a single contributor in touch samples. To determine if TSD could be correctly estimated for mixtures containing a fresh deposit (less than a week old) and an older deposit, this project characterized a series of samples that …
Using A Non-Destructive Method To Estimate The Number Of Contributors And Predict Dna Yield In Touch Dna Mixtures, Christin Lee
Using A Non-Destructive Method To Estimate The Number Of Contributors And Predict Dna Yield In Touch Dna Mixtures, Christin Lee
Master of Science in Forensic Science Directed Research Projects
Touch DNA samples are low templates and often are mixtures, making them typically one of the most difficult types of evidence to interpret. Short tandem repeat analysis is a standard method to estimate the number of contributors and DNA yield for each contributor; however, there are some limitations. Applying a non-destructive pre-DNA analysis technique that provides information about the touch DNA may improve the casework process. Antibody probes to hormones such as testosterone and dihydrotestosterone (DHT), and proteins including cytokeratins (CK) inside epidermal cells, have been demonstrated to produce a personalized signature for human touch cell populations. Testosterone, DHT, and …