Social and Behavioral Sciences Commons^™

Evaluation Of Raman Spectroscopy As A Screening Tool To Predict Dna Recovery Potential In Skeletonized Human Remains, Cody Silverman

Honors Theses

The purpose of this study is to determine if Raman spectroscopy can be used as a rapid and non-destructive screening tool to predict DNA recovery potential for bone, and to explore the correlation between the compositional microstructure of bone and preservation of DNA. The two primary structural components of bone are calcium hydroxyapatite and collagen. It is proposed that by analyzing bone using Raman spectroscopy, the presence, state, and distribution of hydroxyapatite and collagen can be measured, which may be useful in predicting if the sample is viable for DNA analysis. The ultimate goal of this study is to develop …