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Social and Behavioral Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Family, Life Course, and Society

Theses and Dissertations

Theses/Dissertations

2022

Shape analysis

Articles 1 - 2 of 2

Full-Text Articles in Social and Behavioral Sciences

The Relationship Between Thalamic Morphology And Behavioral Features In Amnestic And Aphasic Variants Of Alzheimer's Disease, Holly Rochelle Winiarski Aug 2022

The Relationship Between Thalamic Morphology And Behavioral Features In Amnestic And Aphasic Variants Of Alzheimer's Disease, Holly Rochelle Winiarski

Theses and Dissertations

Background: The presence of AD pathology can result in diverse behavioral phenotypes, including the typical amnestic variant characterized by memory deficits, and an atypical aphasic variant characterized by language deficits. Previous research has identified unique cortical atrophy patterns in each phenotype, though less focus has been drawn to subcortical involvement. The current study sought to dissociate these behavioral phenotypes by characterizing their thalamic volume and shape features using high-dimensional brain mapping procedures. Relationships between brain metrics and specific language and memory deficits were also investigated in aphasic AD and amnestic AD, respectively. Method: Thalamic integrity was examined in aphasic AD …


The Influence Of Sex On Cognitive Control Performance And Frontoparietal Network Integrity In First Episode Psychosis, Kaitlyn Mcfarlane Greer Jun 2022

The Influence Of Sex On Cognitive Control Performance And Frontoparietal Network Integrity In First Episode Psychosis, Kaitlyn Mcfarlane Greer

Theses and Dissertations

Cognitive deficits in first-episode psychosis (FEP) are well documented including deficits in cognitive control, but how sex may influence or impact these cognitive deficits is not well known. Cognitive deficits may impact multiple neural networks, including the fronto-parietal network (FPN). How sex may influence the structural integrity of regions in the FPN is also an important area of research in FEP that may provide further insight into the beginnings of the disease. The current study aimed to examine sexual dimorphisms in structural integrity of the frontoparietal network (FPN) and its role in cognitive control in FEP. A total of 111 …