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Full-Text Articles in Social and Behavioral Sciences
Zonulin As A Mediator Of Psychological Stress And Periodontal Disease, Casey D. Wright
Zonulin As A Mediator Of Psychological Stress And Periodontal Disease, Casey D. Wright
Graduate Theses, Dissertations, and Problem Reports
The prevalence of chronic inflammatory diseases is on the rise. Some have posited the permeability of tight junctions in gastrointestinal epithelium tissues as a potential mechanism for precipitating inflammatory processes throughout the body. Zonulin is the only known modulator of tight junction permeability and has been implicated in numerous chronic inflammatory processes (e.g., proinflammatory cytokine production) and diseases, more generally. The role of zonulin in oral inflammation, however, has yet to be explored. Periodontal disease is the most common oral inflammatory condition and primary perpetrator of tooth loss. Periodontal disease also is associated with a number of other health problems …