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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Do Depressive Symptoms Mediate The Relationship Between Hopelessness And Diurnal Cortisol Rhythm?, Patrick Pössel, Amanda M. Mitchell, Elaine Sjögren, Margareta Kristenson
Do Depressive Symptoms Mediate The Relationship Between Hopelessness And Diurnal Cortisol Rhythm?, Patrick Pössel, Amanda M. Mitchell, Elaine Sjögren, Margareta Kristenson
Faculty Scholarship
Purpose: Research has revealed a well-established relationship of depressive symptoms and hopelessness with a variety of physical illnesses that are associated with a dysfunction of the hypothalamic-pituitary-adrenal-axis. The purpose of this study was to test if depressive symptoms mediate the relationship between hopelessness and cortisol, a measure of the hypothalamic-pituitary-adrenal-axis. Methods: Hopelessness, depressive symptoms, and diurnal cortisol rhythm were measured in 257 adults (128 women and 129 men; age range: 20-74 years) in this cross-sectional study. To test the hypothesis, two linear regression analyses and asymmetrical confidence intervals around the regression weights were conducted. A second set of analyses was …
Do Depressive Symptoms Predict The Incidence Of Myocardial Infarction Independent Of Hopelessness?, Patrick Pössel, Amanda M. Mitchell, Kimmo Ronkainen, George A. Kaplan, Jussi Kauhanen, Maarit Valtonen
Do Depressive Symptoms Predict The Incidence Of Myocardial Infarction Independent Of Hopelessness?, Patrick Pössel, Amanda M. Mitchell, Kimmo Ronkainen, George A. Kaplan, Jussi Kauhanen, Maarit Valtonen
Faculty Scholarship
Depression and hopelessness predict myocardial infarction (MI), but it is unclear whether depression and hopelessness are independent predictors of MI incidents. Hopelessness, depression, and MI incidence rate 18 years later were measured in 2005 men. Cox regressions were conducted with hopelessness and depression serving as individual predictors of MI. Another Cox model examined whether the two predictors predict MI when adjusting for each other. Depression and hopelessness predicted MI in independent regressions but when adjusting for each other, hopelessness, but not depression, predicted MI incidents. Thus, these results suggest that depression and hopelessness are not independent predictors of MI.