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Chronic Restraint Stress Enhances Radial Arm Maze Performance In Female Rats, Rachel E. Bowman, Mark C. Zrull, Victoria N. Luine

Psychology Faculty Publications

Effects of chronic restraint stress (21 and 28 days) on physiological and behavioral parameters in female rats were examined. Total (bound and free) and free corticosterone (CORT) levels were measured at different time points during the stress period. Higher total CORT levels were observed in stressed rats during the stress period but returned to baseline at 15 days poststress. Additionally, free CORT levels decreased across the stress period. Estrous cyclicity was monitored daily in all animals. Stress had no apparent effects on estrous cyclicity, in rats with either normal length or elongated estrous cycles, but stressed females gained less weight …