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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Executive Deficits In Amyotrophic Lateral Sclerosis: Examining The Consequences Of Self-Regulatory Impairment On Quality Of Life, Abbey R. Roach
Executive Deficits In Amyotrophic Lateral Sclerosis: Examining The Consequences Of Self-Regulatory Impairment On Quality Of Life, Abbey R. Roach
University of Kentucky Doctoral Dissertations
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that attacks the motor system and contributes to a range of cognitive and behavioral impairments (e.g., behavioral and emotional disinhibition, planning and problem solving difficulties, impulsivity, attention, and personality change). This executive dysfunction may contribute to selfregulatory impairment across several domains, including cognitive skills, thought processes, emotion regulation, interpersonal skills, and physiology, that may be crucial to the quality of life (QOL), or well being, of patients and their caregivers. Given the relentless course and prognosis of ALS, palliative treatments for ALS should target the full range of self-regulatory deficits. Thirty-seven …
Neuropsychological Correlates And Underlying Cortical Mechanisms Of Working Memory In Moderate To Severe Traumatic Brain Injury, Jessica Ann Clark
Neuropsychological Correlates And Underlying Cortical Mechanisms Of Working Memory In Moderate To Severe Traumatic Brain Injury, Jessica Ann Clark
University of Kentucky Doctoral Dissertations
Functional magnetic resonance imaging (fMRI) is a relatively new tool that has been used to examine patterns of neural activation within those with traumatic brain injuries (TBI). A review of relevant literature is presented, including alterations in activity within the frontal and parietal regions that are thought to be compensatory in nature. In addition, possible explanations for discrepancies within this research are discussed. The current study expands upon previous work by incorporating a delayed-match-to-sample (DMS) task within an event-related paradigm and neuropsychological testing to compare 12 individuals with a history of TBI to 12 control participants with orthopedic injuries (OI). …