Social and Behavioral Sciences Commons^™

Detecting Bacterial Species From Ancient Human Skeletal Samples, Ariel Owens, Daisy Mcgrath, Tsai-Tien Tseng

Symposium of Student Scholars

Diagnosis of tuberculosis (TB) via morphological analysis is difficult and often inconsistent. With next-generation sequencing (NGS), ancient host microbiomes can be subjected to metagenomic analyses for the detection of TB in silico. Suitable bioinformatic workflows are needed for reliable ancient DNA (aDNA) analysis of causative agents. This study aims to enhance available bioinformatic screening methods to create more suitable bioinformatic processes and generate insights in relation to TB.

This research utilizes publicly available NGS data accessed through the Sequence Read Archive (SRA) of the National Center for Biotechnology Information (NCBI). Initial quality control steps included adapter trimming with Trim …

Analysis Of Vertebrae Pathologies Of Grave A650 Chryssi Island, Crete, Greece, Abbey E. Bartmess, Susan Kirkpatrick Smith

Symposium of Student Scholars

This study of multiple, co-mingled adult individuals located in grave A650 on Chryssi Island, Crete, Greece, examines the prevalence of several pathologies of the vertebrae. This grave was built into a collapsed Late Minoan period house (1400-1100 B.C.E.). Grave A650, which likely dates to the 5th – 7th century C.E., shows evidence of being used over a long period of time and may have served as an ossuary. The pathologies of approximately 30 recovered vertebrae, both complete and incomplete, show signs of degenerative joint disease, spondylolisthesis, and body expansion. Researching this data aims to accomplish a comprehensive understanding of what …

Dating The Seals Of Harappa: A Radiocarbon Approach, Grace Abernathy

Symposium of Student Scholars

For many years, Indus seals have puzzled archaeologists with their detailed motifs and undeciphered script. There is no pattern to the relationship between motifs and inscriptions, as each motif has been found scattered across the greater Indus region. In looking at the context of the seals and radiocarbon dating of charcoal, bone, and shell in a singular site, there may be a definitive pattern between certain motifs and the time periods they were used. This study uses contextual analysis to identify chronological patterns of seals discovered at the site of Harappa. Should any patterns arise, this research study could be …

Laryngeal Vocals In Old World Locals: Air Sacs Usage In Bonobos, Chelsea Trenbeath

Symposium of Student Scholars

Except for humans, extant great apes have evolutionarily conserved lateral ventricular air sacs extending from laryngeal saccules. Humans are the only species of Hominidae that lack this anatomical feature attached to the primary vocal apparatus. As we are the only species that produces spoken language, this association has led to hypothesis that the loss of lateral ventricular air sacs was necessary for the evolution of spoken language. However, why these sacs are conserved in all other hominids remains unclear. Computer modeling has indicated that air sacs may increase resonance properties, but there are no data from great apes indicating which …

Detecting Bacterial Species From Ancient Human Skeletal Samples, Ariel Owens, Daisy Mcgrath, Tsai-Tien Tseng

Symposium of Student Scholars

This paleopathological study aims to identify Mycobacterium tuberculosis complex (MTBC), Mycobacterium avium complex (MAC) and other Mycobacterium species in silico from skeletal samples that belonged to 28 Polish individuals in the Neolithic period under PRJNA422903 from the Sequence Read Archive (SRA). After next-generation sequencing (NGS), bioinformatics methods are heavily relied upon for identification of pathogens from complex samples. We implemented a bioinformatics pipeline, with custom-built databases, utilizing the following software tools: Trim Galore! and Kraken2. After adapter trimming, Kraken2 was used for taxonomic classifications. We have found that Mycobacterium is present in all 28 individuals. The average percentage of MAC …

Hematogenous Osteomyelitis In Juveniles: An Examination Of Pathophysiology And Variation In Occurrence In The Archaeological Record And Contemporarily

Symposium of Student Scholars

Osteomyelitis is a general term for a group of diseases that cause inflammation of the bone. In most cases, the cause is infectious agents entering the bloodstream from other infected areas, especially traumatic or surgical wounds (hematogenous osteomyelitis). The main causative agents are Staphylococcus aureus (staph) and Streptococcus (strep). Other causes of osteomyelitis include indirect infection from soft tissue infections or sepsis (Ortner 2003, 181). Although osteomyelitis can occur at any age, hematogenous osteomyelitis is especially prevalent among juveniles. The location of occurrence is related to the timing of development of the growth plates, as well as the vascular supply …