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The Methodological And Diagnostic Applications Of Micro-Ct To Palaeopathology: A Quantitative Study Of Porotic Hyperostosis, Jennifer A. Morgan
The Methodological And Diagnostic Applications Of Micro-Ct To Palaeopathology: A Quantitative Study Of Porotic Hyperostosis, Jennifer A. Morgan
Electronic Thesis and Dissertation Repository
The purpose of this dissertation was to assess the value of micro-CT to palaeopathology for the non-destructive analysis of orbital and cranial porotic hyperostosis, common lesions observed in many archaeological skeletal collections. The objectives of this study were to: 1) identify palaeoepidemiological trends in the prevalence of porotic hyperostosis that may support differential diagnoses, 2) evaluate the reproducibility and reliability of two-dimensional (2D) and three-dimensional (3D) methods of micro-CT data collection for the quantitative analysis of bone microarchitecture, and 3) quantitatively evaluate orbital and cranial porotic hyperostosis to determine the value of micro-CT methods for understanding disease pathogenesis and improving …