Social and Behavioral Sciences Commons^™

Clinician Perspectives On Fistula Mental Health, Victoria K. Leonard

Doctoral Dissertations

Background – Obstetric fistula is a childbirth injury caused by prolonged labor that leads to stillbirth and incontinence, spurring social exclusion and isolation. These layers of trauma put women with fistula at great risk for psychological suffering, which has profound negative socioeconomic impacts on them, their families, and communities. This study captured treatment as usual at Comprehensive Community Based Rehabilitation in Tanzania (CCBRT), the country’s largest provider of fistula care.

Method – Improving holistic fistula treatment requires engaging the clinicians who care for women with fistula. This study aimed to investigate the training, beliefs, and treatment approaches of nurses and …

Serotonin 1a Receptor Modulation On Behavioral Flexibility In Btbr And C57bl/6j Mice, Cassandra Cavazos

Electronic Theses, Projects, and Dissertations

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by a subset of symptoms known as restricted repetitive behaviors (RRBs). RRBs are categorized into both lower order and higher order RRBs, where the latter can be described as behavioral inflexibility. The BTBR T+ tf/J (BTBR) mouse strain has been an extensively used animal model that demonstrate the behavioral symptoms of these individuals, including inflexible behavior. Currently, there are few effective treatments for individuals with ASD that express RRBs. Past research has investigated treatments that target serotonin due its historic involvement in ASD. 8-OH-DPAT (8-hydroxy-2-(di-n-propylamine) tetralin) is a research …

The Role Of 5-Ht6 Receptor Activation In Learning Consolidation, Jasmine Alyssa Robinson

Electronic Theses, Projects, and Dissertations

The focus on serotonergic dysfunction as a contributor to cognitive deficits in disorders such as autism spectrum disorder, Alzheimer's disease, and schizophrenia drives researchers to investigate the functional impact of specific serotonin receptor types on executive functioning. By discerning the potential enhancement or impairment effects, this endeavor seeks to unravel the complex interplay between serotonin receptors and cognitive abilities. Specifically, within the three domains of learning, acquisition, consolidation, and retrieval, we find serotonergic modulation to be pivotal. Recent studies have highlighted the 5-HT6 receptor as a novel target for cognitive enhancement. However, the majority of the research investigates the effects …

Pre-Stimulus Anticipation And Unconscious Fear Learning Disparities In Individuals With Varying Levels Of Anxiety, Anastasiya Rumyantseva Kharlamova

Dissertations, Theses, and Capstone Projects

The current study employed a Pavlovian conditioning paradigm to investigate the influence of pre-stimulus unconscious threat anticipation on subsequent fear responses in associative learning. Additionally, we explored the differences in pre-stimulus anticipation among individuals with varying levels of anxiety. Electrodermal response (EDA) was chosen as a primary measure due to its robustness in fear conditioning paradigms. Moreover, the State-Trait Anxiety Inventory (STAI) was utilized to assess anxiety levels in participants. Twenty-seven subjects were recruited to determine if pre-stimulus skin conductance responses (SCR) would exhibit stimulus-specific patterns influenced by implicit cues (L-shaped configurations) that indicated an upcoming face or a house …

The Archeology Of Adoption: Tracing The Journey From Birth Through Adoption Using Pre-Adoptive Artifacts, Ellen Reeve

Educational Studies Dissertations

Adults adopted in childhood often face a heightened susceptibility to psychological and behavioral challenges compared with their non-adopted peers. Scholars examining this phenomenon associate various factors, including an adoptee’s sense of self as an individual within a complex adoption background. This qualitative study utilized a material engagement theory to explore birth through adoptive narratives among adults adopted in closed settings during childhood. Through participatory research, participants examined a range of artifacts related to maternal relinquishment, encompassing foster and adoption records, original birth certificates, letters, photographs, birthmarks, clothing, hair, scars, and DNA test results. The study focused on understanding these artifacts’ …

Grief Like Mine: A Literature Review Exploring Culturally Informed Grief Work For Black Youth Using Dance/Movement Therapy, Darrell Hyche

Expressive Therapies Capstone Theses

Black American youth are exposed to more death related circumstances than their peers yet are severely underrepresented in literature focused on the broader scope of children’s bereavement. More research and analysis are required to develop and implement culturally relevant interventions as they embark on their grief journey. Dance/movement therapy has the capacity for providing support that is culturally specific and able to meet the developmental levels of children, yet its grief focus work is limited. This literature review aims to bridge the gap between Black grief and dance/movement therapy as a culturally informed practice. An analysis of various forms of …

Towards A New Role Of Mitochondrial Hydrogen Peroxide In Synaptic Function, Cliyahnelle Z. Alexander

Student Theses and Dissertations

Aerobic metabolism is known to generate damaging ROS, particularly hydrogen peroxide. Reactive oxygen species (ROS) are highly reactive molecules containing oxygen that have the potential to cause damage to cells and tissues in the body. ROS are highly reactive atoms or molecules that rapidly interact with other molecules within a cell. Intracellular accumulation can result in oxidative damage, dysfunction, and cell death. Due to the limitations of H₂O₂ (hydrogen peroxide) detectors, other impacts of ROS exposure may have been missed. HyPer7, a genetically encoded sensor, measures hydrogen peroxide emissions precisely and sensitively, even at sublethal levels, during …

Mate Guarding Against Strong Men Displaying Affiliative And Aggressive Humor, Jacob Pauley

Biological Sciences Undergraduate Honors Theses

Mate retention behaviors serve to discourage partner defection from a current pairbond. Such behaviors are oftentimes more prevalent toward intrasexual rivals exhibiting physical and behavioral cues implicating that rival as an optimal mate. Among these features in men are their upper body strength, a feature diagnostic of heritable fitness, and men's ability to produce humor, a cue to their social competence. This study considered the intersection of these desirable features in shaping men's mate retention behavior toward an intrasexual rival. After learning of a hypothetical interloper exhibiting high or low upper body strength while similarly using humor in an affiliative …

Impact Of Perinatal Escitalopram Exposure On Adolescent Behavior, Jessica Bezenah - Bottorff

Electronic Theses, Projects, and Dissertations

Escitalopram (EST), a selective serotonin reuptake inhibitor (SSRI), is an antidepressant frequently used during pregnancy, yet there is limited knowledge of its long-term effects on maternal use. Past studies suggest that maternal exposure may adversely affect the fetus, which may be due to the hyperserotonergic environment caused by the nature of SSRIs during early development. Modifications of the serotonergic system in offspring during certain critical periods of development may result in long-term behavioral and cognitive changes in adulthood. Further, recent human studies have demonstrated that prenatal exposure to SSRIs in humans may increase susceptibility to autism spectrum disorder (ASD) and …

Examining The Effects Of Menstrual Cycle Phase And Hormonal Contraceptive Use On Women's Sleep, Charles Ethan Coombs

Psychological Science Undergraduate Honors Theses

Women overrepresent men for sub-optimal sleep, a consequence of hormone fluctuation in the menstrual cycle affecting sleep regulatory pathways. While research has examined the prevalence of sub-optimal sleep through cycle phases, little research has examined how hormonal contraceptives (HC’s) could similarly affect women’s sleep, while also neglecting to utilize subjective sleep measures. In this study, we examine subjective sleep quality among naturally cycling (NC) women, women using different HC types, and between active and inactive phase pill users by subjecting 463 women to a subjective sleep battery. We hypothesized that HC users would report more sub-optimal sleep than NC women. …

Examining The Effects Of Acute And Chronic Stress On The Interrogative Suggestibility Of Young Adults, Claudia Cota

Open Access Theses & Dissertations

High-stress situations, like police interrogations, can hinder an individual's decision-making and critical-thinking ability (Liston et al., 2009), making them more susceptible to suggestive or leading messages during questioning. While research on suggestibility mainly focuses on children and adolescents, young adults may also be vulnerable to suggestion because of their sensitivity to social feedback (Blakemore & Mills, 2014; Redlich & Goodman, 2003). Since the legal consequences of suggestibility for young adults are more severe than for children or adolescents, it is essential to examine the role of stress in young adults' suggestibility. The present study used objective and subjective methods to …

Stress-Induced Oxytocin Reactivity As A Predictor Of Daily Support Seeking After Stress, Cecile Sunahara

Psychology Theses and Dissertations

The current study examined whether stress-induced peripheral oxytocin (OT) was associated with support-seeking behaviors after stress in daily life. Healthy male and female participants (N=94) performed a standardized laboratory stressor, the Trier Social Stress Test (TSST), and then completed two weeks of daily assessments of support seeking after stress. In line with preregistered hypotheses, plasma OT reactivity to the TSST (indexed as the area under the curve with respect to increase; AUCi) was associated with more frequent support seeking behaviors following stress in daily life. Moreover, this association was stronger for individuals with higher levels of attachment anxiety, relative to …

Exploring Auditory Thalamocortical Pathways In Autism Spectrum Disorder, Caitlin Dyer

University of New Orleans Theses and Dissertations

Thalamocortical tracts related to language have rarely been examined in autism spectrum disorder (ASD). We examined the medial geniculate nucleus (MGN), Heschl’s gyrus (HG), and planum temporale (PT) volumes, and the connections from MGN to HG and MGN to PT, using MRIs from 39 children with ASD (20 with receptive language impairment, 19 without) and 20 typically developing controls, aged 5-17 years. In children with ASD without language impairment, MGN volume was positively correlated with receptive language scores. Additionally, the thalamus was smaller in children with ASD with language impairment, correlating negatively with receptive language scores in this group. Left …

The Walking Threat: Traits Of Pathogen Avoidance, Pathogen Threat Proximity And Functional Flexibility, Lahai Alexander Massaquoi Wicks

Doctoral Dissertations

The threat of infection to humans is unwavering, and it is increased through social interaction, which human life is based around. This has been demonstrated through the recent SARS-CoV-2 pandemic, where social distancing was recommended to prevent the spread of the virus. Therefore, it is important to understand both the behavioral and physiological defenses that we possess against illness. However, the characteristics of the relationship between the behavioral immune system (BIS) and the physiological immune system (PIS) are still murky. This dissertation sought to better understand how the BIS considers the costs of mounting an immune response via functional flexibility …

The Role Of Awe In Risk-Taking And The Exploration Of The Unknown, Matthew Thomas Richesin

Doctoral Dissertations

Much has been learned about awe through scientific inquiry in the last twenty years, however, few researchers have looked to understand the adaptive function. Recent work has suggested that the function of awe is cognitive in nature. This view argues that the function awe plays is linked to how individuals respond to uncertainty. This approach proposes that awe should be linked to various epistemic dispositions such as curiosity, impulsivity, intolerance to uncertainty, and existential thinking. It further suggests that awe will have a distinct effect on risk-taking behaviors compared to fear and curiosity. The current project consists of three studies …

The Relationship Between Cognitive Impairment In Psychiatric Patients And Readmission Rate To An Inpatient Facility, Cherilyn Isis Schuff

Theses and Dissertations

The primary intention of this study was to further understand the impact of assessing cognitive impairment in psychiatric patients, as a mediating factor on readmission rates. Mild cognitive dysfunction impacts a patient’s functional outcomes (Bowie & Harvey, 2006; Davis et al., 2012; Marcantonio, et al., 2001). Little information exists to guide best practices in the treatment of adults with cognitive impairment who are hospitalized for acute conditions (Davis et al., 2012). A cognitive impairment may impact patient prognosis and ability to function outside of a setting focused on stabilization. Neuropsychological testing is a valuable tool in predicting a patient’s cognitive …

Cognitive Functioning In Well-Controlled Asthma, Erin Walsh

West Chester University Doctoral Projects

Asthma is a common lung disease that impacts lung functioning through inflammatory based mechanisms. Past research suggests that decreased blood oxygenation due to asthma attacks may impair cognitive capabilities (Irani et al., 2017). Moreover, the observed differences in cognition between those with and without asthma may be associated with disease severity or asthma control respectively in asthma populations. The current study explored differences in cognitive functioning between college students with and without self-reported asthma. Sociodemographic data, self-reported asthma severity, and measures of asthma control were collected. The current study did not find significant differences in measures of cognitive efficiency between …

Nobody's Perfect: Examining The Relationship Between Parenting Traits And Perfectionism And The Impact Of Maladaptive Versus Adaptive Perfectionism On Cortisol Regulation After Receiving Criticism, Olivia G. Baron

MSU Graduate Theses

The trait of perfectionism has been related to both internalizing and externalizing psychopathology. Parenting traits, and attachment tendencies affect how children develop relationships and impact them into their adult lives. Parents have a large impact on their child’s personality traits, coping styles, and modeling reactions to outward criticism. Criticism, especially criticism delivered by parents, has been linked to perfectionism. Perfectionism often involves a self-critical component, though perfectionists have not been studied to examine stress responses (e.g. cortisol change) when receiving criticism. This study examined the relationships between parenting traits (positive and negative) and perfectionism (adaptive and maladaptive). Cortisol change scores …

Strength In A Pinch: Sex Differences In Detection Of And Responses To Threats, Lorena Mesquita Ragonesi

Honors Theses

Handgrip strength is a sexually dimorphic marker of muscle activation and force production. Males consistently demonstrate greater baseline maximal handgrip strength than females. Various factors can influence an individual’s handgrip strength; interestingly, threat detection can increase handgrip strength. Recently, Kawakami et al. (2018) reported that mortality salience increases handgrip strength in men, but not in women. To explain this finding, they argued that physical strength is a more salient goal for men than women, whereas women should strive for beauty as a strategy to avoid harm. While they did find this interesting sex difference in their study, we had concerns …

The Effects Of Early Developmental Co-Exposure To Alcohol And Nicotine Via E-Cigarettes On Anxiety- And Motor-Related Behaviors In Mice, Carley Cirafesi

West Chester University Master’s Theses

Thirty percent of people who report consumption of alcohol while pregnant simultaneously report consuming nicotine. Prenatal co-exposure to alcohol and nicotine has increased with the popularity of electronic cigarettes due to their presumed safety, yet e-cigarette use may have a greater impact on fetal development than traditional cigarettes. Prenatal exposure to alcohol or nicotine is associated with increased anxiety-related behaviors and impaired motor coordination later in life, yet it is unknown whether prenatal co-exposure to alcohol and nicotine exacerbates these effects, particularly via e-cigarettes. This project examined the effects of co-exposure to alcohol and nicotine via e-cigarettes during early development …

A Comparison Of Symptom Profiles In Probands With 16p11.2 Deletion And Duplication Syndromes: Repetitive Behavior And Psychosis Proneness, Adrianna Rakauskas

Honors Theses

The present study examines two classes of behavior in probands with the 16p11.2 duplication and deletion: repetitive behavior and psychosis spectrum behavior. It was hypothesized that 1.) deletion and duplication cases will differ significantly in the means and profiles of repetitive behaviors across five subscales and 2.)16p11.2 duplication cases will exhibit more schizotypal traits than the deletion cases. Data on 94 total participants was obtained from the Simmons Variation Individuals Project. Three scales were used to measure behavior: the Childhood Routines Inventory-Revised, the Childhood Oxford-Liverpool Inventory of Feelings and Experiences, and the Child Behavior Checklist. Data analysis was conducted using …

Repeated Treatment With 5-Ht1a And 5-Ht1b Receptor Agonists: Evidence Of Tolerance And Behavioral Sensitization, Jordan Taylor

Electronic Theses, Projects, and Dissertations

Serotonin has been found to regulate several cognitive and physiological functions, and its role in depression and other neuropsychiatric disorders has been a focus of research. More specifically, a wealth of research regarding serotonin focuses on serotonergic medications in the treatment of neuropsychiatric disorders, such as depression and anxiety, and stimulates the 5-HT_1A and 5-HT_1B receptors. Within the last decade, there has been an increase in prescriptions of psychotropic medication for children, however, the efficacy and adverse effects of these drugs have not been evaluated in younger populations. While antidepressants reduce symptoms of depression in adults, they are …

Cerebrospinal Fluid Biomarkers Not Associated With Neurologic Compromise Among Mild Cognitively Impaired Reverters With Parkinson's Disease, Cameron Ryczek

Electronic Theses, Projects, and Dissertations

Parkinson's Disease (PD) is a neurodegenerative disease characterized by motor (e.g. tremors) and non-motor symptoms (e.g. cognitive impairment). PD patients' change in cognitive functioning can be observed using the following classifications: cognitively intact, mild cognitive impairment (MCI), or dementia (PDD). MCI has many subtypes, one of which is MCI reversion which is defined as those with MCI at one time point reverting to cognitively intact later. While there is limited research into the utility of MCI reversion and its relationship with cerebrospinal fluid (CSF) biomarkers in PD, this study will begin to elucidate this relationship. To this end, data from …

Identifying Trauma Related Predictors Of Dissociation In Maltreated Youth, Amanda L. Mraz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Maltreated youth who experience traumatic dissociation are at an increased risk for various psychopathological difficulties. Much is still unknown about the machinations behind experiences of dissociation post-trauma. This study aimed to identify variables that place maltreated youth at risk for experiencing traumatic dissociation (e.g., dissociative amnesia, absorption and imaginative involvement, passive influence, depersonalization and derealization, and total adolescent dissociative experiences symptoms (A-DES)). Investigatory variables included demographic (e.g., age, gender, and racial identity), cognitive (e.g., resiliency and posttraumatic cognitions), and psychological (e.g., posttraumatic stress disorder symptoms (PTSD) and anxiety) factors. Classification and regression tree (CART) analysis was utilized to observe the …

You Hurt My Feelings: Autonomic And Behavioral Responses To Social Exclusion And The Moderating Effect Of Psychopathic Traits, Liat Kofler

Dissertations, Theses, and Capstone Projects

Humans have a fundamental need to form and maintain social connections, and thus experiencing social exclusion is extremely distressing as it threatens this basic human need. Individuals who are socially excluded often respond aggressively, not only towards their ostracizers but also towards innocent bystanders, with ostracism being implicated in extreme acts of violence such as school shootings. However, individual differences in behavior exist within the context of social exclusion as not everyone responds aggressively after being ostracized. Identifying risk factors for retaliatory aggressive behavior following experiences of social exclusion may facilitate the development of targeted interventions aimed at mitigating such …

The Effects Of Transcranial Direct Current Stimulation (Tdcs) On Facial Expression Approach/Avoidance In College Students And Faculty With Broad Autism Phenotype, Nicole R. Baker

Electronic Theses and Dissertations

Transcranial Direct Current Stimulation (tDCS) has been proposed as an alternative noninvasive therapy for individuals with autism. This study trained brain activity in college students and / or faculty with Broad Autism Phenotype (BAP) while eye tracking data was collected. The purpose of this study was to determine if tDCS training to the frontal lobes could increase approach toward social interactions in adults classified as BAP as demonstrated by eye-tracking measures in response to faces and gaze fixation. The study included 21 total participants recruited from the Science, Technology, Engineering, and Math (STEM) courses / professions at a Regional East …

Examination Of Performance Validity And The Relationship To Cognition And Symptoms In Schizophrenia Spectrum Disorders, Erick A. Rogers

UNLV Theses, Dissertations, Professional Papers, and Capstones

Approximately one-in-five individuals with psychotic disorders (i.e., schizophrenia spectrum disorders [SSD]) fail performance validity indicators (PVIs) during neurocognitive testing. Ensuring the validity of neurocognitive test results is necessary if the test scores are to be of use for diagnostic consideration, intervention selection and planning, predicting outcomes, and following changes in cognition over time in response to intervention, spontaneous recovery, or disease progression. PVIs are designed to require only a minimum level of engagement with the evaluation, which means nearly everyone is expected to “pass,” even those with moderate to severe brain damage. Traditional interpretations of PVI failure suggest a noncredible …

Adverse Childhood Experiences(Aces) And Nonverbal Reasoning Skills, Monika Malinowska

Dissertations

Severe stress and interpersonal traumatic experience in childhood have a cascade effect on an individual's physical and mental health. There is evidence that people with complex adverse childhood experiences have diminished cognitive abilities. However, there are few studies on the effects of Adverse Childhood Experiences (ACE) on non-verbal reasoning skills. This study aimed to assess the relationships between ACEs, non-verbal reasoning skills, and academic achievement.

Sucrose Demand And Essential Value In Mice With Early-Life Exposure To Risperidone, Megan Federoff

LSU Master's Theses

Second-generation antipsychotics (SGAs), such as risperidone, are widely prescribed to children, but the long-term effects of SGA treatment are not well understood. This study investigated the impact of early-life risperidone treatment on sucrose demand in mice in adulthood. Mice were administered risperidone or vehicle from postnatal day (PND) 33 to 60 and trained in adulthood (>PND 120) to nose poke for a sucrose solution reinforcer. The fixed ratio (FR) value (the number of responses required to produce sucrose delivery; the “price” of sucrose) was varied from 1 to 45, and the resulting consumption versus FR value data were analyzed …

Working Memory And Language Associations In Children With Autism Spectrum Disorder, Megan A. Goldfarb

University of New Orleans Theses and Dissertations

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social communication and interaction, with repetitive behaviors or specialized interests. A range of language abilities is seen in ASD, with some having typical abilities and others severe impairments. Working memory (WM) deficits have also been found in some children with ASD. In typically developing, as well as non-ASD children with language deficits a strong relationship has been found between WM and language abilities. Although both language and WM deficits are often seen in ASD, the relationship between these deficits has been underexplored. The objective of this study is …