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Social and Behavioral Sciences Commons

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Biological Psychology

Theses and Dissertations

Depression

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Full-Text Articles in Social and Behavioral Sciences

The Impact Of Exercise On Adolescents With Depression: A Systematic Review Of The Literature, Matthew P. Kloeris Jan 2021

The Impact Of Exercise On Adolescents With Depression: A Systematic Review Of The Literature, Matthew P. Kloeris

Theses and Dissertations

The purpose of the present study was to summarize and synthesize the research that pertains to the impact of aerobic exercise on adolescents with depression. This review addressed aerobic exercise as a mental health treatment, such as differences between (a) post-intervention and follow-up response and remission rates; (b) exercise in lieu of psychotherapy or exercise as an adjunct to psychotherapy; and (c) response and remission rates amongst minority gender and racial and ethnic groups. The search results produced a total of 2,122 articles. Of which, eight articles were eligible for the present systematic review. Based on the results, it appears …


Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith Jan 2017

Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith

Theses and Dissertations

Major depressive disorder (MDD) is a widespread psychiatric disorder that affects millions of people worldwide and is hypothesized to occur due to impairments in several neurotransmitter systems, including the monoaminergic and glutamatergic neurotransmitter systems. Antidepressant medications targeting multiple monoamine neurotransmitters have been shown to be effective for the treatment of depression. Racemic amisulpride is an atypical antipsychotic that has been used at low doses to treat dysthymia, a mild form of depression, and functions as an antagonist at DA2/3, 5-HT2B, and 5-HT7 receptors. Recent preclinical studies have suggested that the S(+) isomer may be more …


Behavioral Phenotyping Of Vmat1 Knockout Mice: Relevance To Neuropsychiatric Disorders, Kevin A. Webster Ph.D. Jan 2016

Behavioral Phenotyping Of Vmat1 Knockout Mice: Relevance To Neuropsychiatric Disorders, Kevin A. Webster Ph.D.

Theses and Dissertations

Schizophrenia is a debilitating mental disorder that causes a large economic burden and is prevalent across all cultures and countries around the world. Although both environmental factors and genetics are known to play an important role in the etiology of schizophrenia, the exact role of genetics and its interaction with environmental factors in an individual’s predisposition to develop schizophrenia is poorly understood. Schizophrenia is characterized by symptoms that include positive symptoms (e.g. delusions, hallucinations, disorganized thinking and speech), negative symptoms (e.g. avolition, anhedonia, depressive-like behavior), and cognitive dysfunctions (e.g. executive functioning deficits in learning and memory, attention, and vigilance). Genomic …