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Social and Behavioral Sciences Commons

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Biological Psychology

Gettysburg College

2011

8-OH-DPAT

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Full-Text Articles in Social and Behavioral Sciences

Serotonin, Motivation, And Playfulness In The Juvenile Rat, Stephen M. Siviy, Loren M. Deron, Chelsea R. Kasten Oct 2011

Serotonin, Motivation, And Playfulness In The Juvenile Rat, Stephen M. Siviy, Loren M. Deron, Chelsea R. Kasten

Psychology Faculty Publications

The effects of the selective 5HT1A agonist 8-OH-DPAT were assessed on the play behavior of juvenile rats. When both rats of the test pair were comparably motivated to play, the only significant effect of 8-OH-DPAT was for play to be reduced at higher doses. When there was a baseline asymmetry in playful solicitation due to a differential motivation to play and only one rat of the pair was treated, low doses of 8-OH-DPAT resulted in a collapse of asymmetry in playful solicitations. It did not matter whether the rat that was treated initially accounted for more nape contacts or fewer …