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Full-Text Articles in Social and Behavioral Sciences
The Effects Of Escalated Cocaine Intake On Decision-Making Dynamics, Mcallister Stephens
The Effects Of Escalated Cocaine Intake On Decision-Making Dynamics, Mcallister Stephens
Theses and Dissertations--Psychology
Cocaine Use Disorder (CUD) is characterized partly by the use of cocaine at the expense of other alternatives, in other words, it is a decision-making pathology (Kalivas & Volkow, 2005). Concurrent choice tasks assess decision-making in a dynamic scenario that more closely resembles real life. Value-based decision-making is an important facet of understanding the addictive properties of drugs of abuse. In order to compare two value-based theories of addiction (habit theory and relative value theory), a concurrent choice task was run in tandem with an escalation procedure. First, animals were trained on a choice task until stable, then trained on …
Development Of An Avian Model For Identifying Individual Differences In Drug Vulnerability, Beth A. Rice
Development Of An Avian Model For Identifying Individual Differences In Drug Vulnerability, Beth A. Rice
Theses and Dissertations--Psychology
The attribution of incentive salience to cues that become associated with drugs of abuse is a critical characteristic of individuals who may be vulnerable to drug addiction. Rodents with the propensity to sign track are thought to be vulnerable to drug abuse. The goal of the current work was to investigate whether sign trackers (STs) would acquire cocaine conditioned place preference (CPP) to a discrete cue using an avian species. In Experiment 1, sign and goal trackers (GTs) were first identified using a one third rank order split. Following identification, cocaine-CPP was conducted with a discrete cue in each end …