Environmental Health and Protection Commons^™

Fundulus As The Premier Teleost Model In Environmental Biology: Opportunities For New Insights Using Genomics, Karen G. Burnett, Lisa J. Bain, William S. Baldwin, Gloria V. Callard, Sarah Cohen, Richard T. Di Giulio, David H. Evans, Marta Gómez-Chiarri, Mark E. Hahn, Cindi A. Hoover, Sibel I. Karchner, Fumi Katoh, Deborah L. Maclatchy, William S. Marshall, Joel N. Meyer, Diane E. Nacci, Marjorie F. Oleksiak, Bernard B. Rees, Thomas D. Singer, John J. Stegeman, David W. Towle, Peter A. Van Veld, Wolfgang K. Vogelbein, Andrew Whitehead, Richard N. Winn, Douglas L. Crawford

United States Environmental Protection Agency: Staff Publications

A strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an extensive body of work examining the adaptive responses of Fundulus species to environmental conditions, and describe how this research has contributed importantly to our understanding of physiology, gene regulation, toxicology, and ecological and evolutionary genetics of teleosts and other vertebrates. These explorations have reached a critical juncture at which advancement is hindered by the lack of genomic resources for these …