Physical Sciences and Mathematics Commons^™

An Analysis Of Risk Reduction Choices In Dcis Breast Cancer Patients, Lauren Soltesz

Statistics

The main focus of this paper was to evaluate possible demographic and clinical characteristics associated with a woman’s choice of breast conserving surgery (BCS), unilateral mastectomy (ULM), or bilateral risk reduction mastectomy (BRRM). The cohort consisted of patients presenting to the City of Hope National Medical Center with ductal carcinoma in situ breast cancer who elected to have cancer directed surgery (N=305). Analyses to examine associations of patient characteristics with type of surgery were conducted using a multinomial logistic regression. Results showed that older women were more likely to choose breast conserving surgery over bilateral risk reduction mastectomy than younger …

Metabr: An R Script For Linear Model Analysis Of Quantitative Metabolomic Data, Ben Ernest, Jessica R. Gooding, Shawn R. Campagna, Arnold M. Saxton, Brynn H. Voy

Chemistry Publications and Other Works

Background

Metabolomics is an emerging high-throughput approach to systems biology, but data analysis tools are lacking compared to other systems level disciplines such as transcriptomics and proteomics. Metabolomic data analysis requires a normalization step to remove systematic effects of confounding variables on metabolite measurements. Current tools may not correctly normalize every metabolite when the relationships between each metabolite quantity and fixed-effect confounding variables are different, or for the effects of random-effect confounding variables. Linear mixed models, an established methodology in the microarray literature, offer a standardized and flexible approach for removing the effects of fixed- and random-effect confounding variables from …

A Descriptive Study Of Childhood Cancer Statistics: Montgomery County, Jamie L. Hartig

Master of Public Health Program Student Publications

Objective: This research describes childhood cancer and identifies variances in childhood cancer statistics in the United States, Ohio, and Montgomery County.

Methods: This is a descriptive analysis of childhood cancer statistics using the Ohio Cancer Incidence Surveillance System (OCISS) (Ohio Department of Health, 2010) and CDC Wonder database (United States Department of Health and Human Services [USDHHS], Centers for Disease Control and Prevention [CDC], & National Cancer Institute [NCI], 2008 & 2011.) Cancer incidences between white children and black children were compared for the years 1999-2009. The OCISS database was also used to compare vital status by race, cancer stage …

The Dirty “S” Word: Innovative Teaching Techniques For Counselor Educators Facilitating Learning In Statistics And Research, Rebecca L. Tadlock-Marlo, Megan Michalak

Faculty Research & Creative Activity

Innovative pedagogy will be presented and discussed to help make research a less painful class to both teach and learn. Foci include teaching methods, potential assignments, and suggestions for activities to help facilitate a more fluid learning process for counselors. Attendees will explore aspects of helping students overcome their fear of both statistics and research.

Slides: Draft Power In Developing Country Agriculture--South Asia, Arjun Makhijani

2012 Energy Justice Conference and Technology Exposition (September 17-18)

Presenter: Dr. Arjun Makhijani, President, Institute for Energy and Environmental Research (IEER)

13 slides

The Gaise College Report: The American Statistical Association Meets Sound Pedagogy In Central Virginia, Beverly Wood

Publications

Research in undergraduate statistics education often centers on the introductory course required for a large percentage of college students. While acknowledging the diverse setting, audience, and purpose of introductory courses, existing research assumes that courses offered by different disciplines share the same goals and teaching practices. The purpose of this study is to examine the objectives for student outcomes and pedagogical delivery of introductory statistics courses in various academic departments to provide explicit evidence for this assumption. The American Statistical Association’s Guidelines for Assessment and Instruction in Statistics Education (GAISE) are meant to apply to all introductory courses. The College …

From Unbiased Numerical Estimates To Unbiased Interval Estimates, Baokun Li, Gang Xiang, Vladik Kreinovich, Panagios Moscopoulos

Departmental Technical Reports (CS)

One of the main objectives of statistics is to estimate the parameters of a probability distribution based on a sample taken from this distribution. Of course, since the sample is finite, the estimate X is, in general, different from the actual value x of the corresponding parameter. What we can require is that the corresponding estimate is unbiased, i.e., that the mean value of the difference X - x is equal to 0: E[X] = x. In some problems, unbiased estimates are not possible. We show that in some such problems, it is possible to have interval unbiased estimates, i.e., …

Mathematics And The Hunger Games, Michael A. Lewis

Journal of Humanistic Mathematics

The Hunger Games plot features a dystopian future in which twelve outer districts are oppressed by a centralized capital. The story focuses on the heroism of a sixteen-year-old girl named Katniss and how she tries to rise above the oppression that she experiences. It also features a special lottery and other twists that are sources of mathematical interest. This essay focuses on some of the mathematical issues raised by The Hunger Games in an effort to show that this story can be used to teach students (as well as other interested parties) some important concepts from mathematics.

Adaptive Randomization Designs, Jenna Colavincenzo

Statistics

Adaptive design methodologies use prior information to develop a clinical trial design. The goal of an adaptive design is to maintain the integrity and validity of the study while giving the researcher flexibility in identifying the optimal treatment. An example of an adaptive design can be seen in a basic pharmaceutical trial. There are three phases of the overall trial to compare treatments and experimenters use the information from the previous phase to make changes to the subsequent phase before it begins.

Adaptive design methods have been in practice since the 1970s, but have become increasingly complex ever since. One …

Lifestyle Choices In Relation To Bmi And Blood Pressure, Shawna Perry

Statistics

Cal Poly currently has one of the largest ongoing university health studies in the United States. Launched in Fall 2009, the Cal Poly FLASH study, led by the Kinesiology department and STRIDE, is a longitudinal study that tracks the classes of 2013 and 2014 through online surveys and physical assessments. The data collected covers various areas such as perceived health, lifestyle choices, and actual physical health.

My project analyzed the FLASH data to investigate the relationship between various perceived variables and actual health measures for Cal Poly freshmen. The motivation for this analysis was an interest in both diet and …

Decomposition Of High Frequency Data In Components: Visualization And Interpretative Models, Carlo Drago

Carlo Drago

No abstract provided.

Using The R Library Rpanel For Gui-Based Simulations In Introductory Statistics Courses, Ryan M. Allison

Statistics

As a student, I noticed that the statistical package R (http://www.r-project.org) would have several benefits of its usage in the classroom. One benefit to the package is its free and open-source nature. This would be a great benefit for instructors and students alike since it would be of no cost to use, unlike other statistical packages. Due to this, students could continue using the program after their statistical courses and into their professional careers. It would be good to expose students while they are in school to a tool that professionals use in industry. R also has powerful …

Constructing Phylogenetic Trees Using Maximum Likelihood, Anna Cho

Scripps Senior Theses

Maximum likelihood methods are used to estimate the phylogenetic trees for a set of species. The probabilities of DNA base substitutions are modeled by continuous-time Markov chains. We use these probabilities to estimate which DNA bases would produce the data that we observe. The topology of the tree is also determined using base substitution probabilities and conditional likelihoods. Felsenstein [2] introduced this method of finding an estimate for the maximum likelihood phylogenetic tree. We will explore this method in detail in this paper.

A Note On The Indeterminacy And Arbitrariness Of Pena’S Method Of Construction Of Synthetic Indicators, Sudhanshu K. Mishra

Sudhanshu K Mishra

In this paper we demonstrate that Pena’s method of construction of a synthetic indicator is very sensitive to the order in which the constituent variables (whose linear aggregation yields the synthetic indicator) are arranged. Since m number of constituent variables may be arranged in m-factorial ways, even a moderately large m can give rise to a very large number of synthetic indicators from which one cannot choose the one which best represents the constituent variables. Given that an analyst has too little information as to the order in which a sizeable number of constituent variables must be arranged so as …

Application Of A Data Mining Framework For The Identification Of Agricultural Production Areas In Wa , Yunous Vagh, Leisa Armstrong, Dean Diepeveen

Leisa Armstrong

This paper will propose a data mining framework for the identification of agricultural production areas ill WA. The data mining (DM) framework was developed with the aim of enhancing the analysis of agricultural datasets compared to currently used statistical methods. The DM framework is a synthesis of different technologies brought together for the purpose of enhancing the interrogation of these datasets. The DM framework is based on the data, information, knowledge and wisdom continuum as a horizontal axis, with DM and online analytical processing (OLAP) forming the vertical axis. In addition the DM framework incorporates aspects of data warehousing phases, …

Incorporating Quantitative Reasoning In Common Core Courses: Mathematics For The Ghost Map, John R. Jungck

Numeracy

How can mathematics be integrated into multi-section interdisciplinary courses to enhance thematic understandings and shared common readings? As an example, four forms of quantitative reasoning are used to understand and critique one such common reading: Steven Berlin Johnson’s "The Ghost Map: The Story of London's Most Terrifying Epidemic - and How it Changed Science, Cities and the Modern World" (Riverhead Books, 2006). Geometry, statistics, modeling, and networks are featured in this essay as the means of depicting, understanding, elaborating, and critiquing the public health issues raised in Johnson’s book. Specific pedagogical examples and resources are included to illustrate applications and …

Period Life Tables: A Resource For Quantitative Literacy, Thomas J. Pfaff, Stanley Seltzer

Numeracy

A period life table provides an estimate of the probability that a person will die at a particular age. Using data available online, we examine tables of expected years to live for males and females against age for three populations: the United States in 2007, the U.S. at the turn of the twentieth century, and the Roman Empire. Scatter plots of males and females for each population show how life expectancy increases with age (e.g., U.S. 2007: 50 year-old female > 40 year-old female > 45 year-old male). The three data sets allow historical comparisons (e.g., of gender disparity, larger now; of …

The Dirty “S” Word: Innovative Teaching Techniques For Counselor Educators Facilitating Learning In Statistics And Research, Rebecca L. Tadlock-Marlo, Megan Michalak

Rebecca L Tadlock-Marlo

Innovative pedagogy will be presented and discussed to help make research a less painful class to both teach and learn. Foci include teaching methods, potential assignments, and suggestions for activities to help facilitate a more fluid learning process for counselors. Attendees will explore aspects of helping students overcome their fear of both statistics and research.

Student Fact Book, Fall 2012, Thirty-Sixth Annual Edition, Wright State University, Office Of Student Information Systems, Wright State University

Wright State University Student Fact Books

The student fact book has general demographic information on all students enrolled at Wright State University for Fall Quarter, 2012.

Investigating Forest Inventory And Analysis-Collected Tree-Ring Data From Utah As A Proxy For Historical Climate, R. Justin Derose, Shih-Yu (Simon) Wang, John D. Shaw

Wasatch Dendroclimatology Research

Increment cores collected as part of the periodic inventory in the Intermountain West were examined for their potential to represent growth and be a proxy for climate (precipitation) over a large region (Utah). Standardized and crossdated time-series created from pinyon pine (n=249) and Douglas-fir (n=274) increment cores displayed spatiotemporal patterns in growth differences both between species and by region within Utah. However, the between-species interrelationship of growth was strong over much of the state and indicated both species respond similarly to climate variations. Indeed, pinyon pine and Douglas-fir exhibited a significant and spatially coherent response to instrumental precipitation data. Previous …

When 10 Trials Are Better Than 1000: An Evidentiary Perspective On Trial Sampling, Edward K. Cheng

Vanderbilt Law School Faculty Publications

In many mass tort cases, separately trying all individual claims is impractical, and thus a number of trial courts and commentators have explored the use of statistical sampling as a way of efficiently processing claims. Most discussions on the topic, however, implicitly assume that sampling is a “second best” solution: individual trials are preferred for accuracy, and sampling only justified under extraordinary circumstances. This Essay explores whether this assumption is really true. While intuitively one might think that individual trials would be more accurate at estimating liability than extrapolating from a subset of cases, the Essay offers three ways in …

The Dirty “S” Word: Innovative Teaching Techniques For Counselor Educators Facilitating Learning In Statistics And Research, Rebecca Tadlock-Marlo, Megan Michalak

Faculty Research & Creative Activity

Innovative pedagogy will be presented and discussed to help make research a less painful class to both teach and learn. Foci include teaching methods, potential assignments, and suggestions for activities to help facilitate a more fluid learning process for counselors. Attendees will explore aspects of helping students overcome their fear of both statistics and research.

Changes Across 25 Years Of Statistics In Medicine, Johanna S. Hardin

Pomona Faculty Publications and Research

[This piece is a series of interviews with giants in the field of medicine on their views of how statistics is changing medicine. I interviewed the editor of the New England Journal of Medicine, a preeminent doctor/researcher of lung cancer, the director of the LA County Department of Public Health, and a Harvard statistician who sits on the editorial board of the New England Journal of Medicine.]

Medicine, Statistics, And Education: The Inextricable Link, Katharine K. Brieger '11, Johanna S. Hardin

Pomona Faculty Publications and Research

No abstract provided.