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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Bayesian Analytical Approaches For Metabolomics : A Novel Method For Molecular Structure-Informed Metabolite Interaction Modeling, A Novel Diagnostic Model For Differentiating Myocardial Infarction Type, And Approaches For Compound Identification Given Mass Spectrometry Data., Patrick J. Trainor Aug 2018

Bayesian Analytical Approaches For Metabolomics : A Novel Method For Molecular Structure-Informed Metabolite Interaction Modeling, A Novel Diagnostic Model For Differentiating Myocardial Infarction Type, And Approaches For Compound Identification Given Mass Spectrometry Data., Patrick J. Trainor

Electronic Theses and Dissertations

Metabolomics, the study of small molecules in biological systems, has enjoyed great success in enabling researchers to examine disease-associated metabolic dysregulation and has been utilized for the discovery biomarkers of disease and phenotypic states. In spite of recent technological advances in the analytical platforms utilized in metabolomics and the proliferation of tools for the analysis of metabolomics data, significant challenges in metabolomics data analyses remain. In this dissertation, we present three of these challenges and Bayesian methodological solutions for each. In the first part we develop a new methodology to serve a basis for making higher order inferences in metabolomics, …


Fm Radio Signal Propagation Evaluation And Creating Statistical Models For Signal Strength Prediction In Differing Topographic Environments, Timothy Land May 2018

Fm Radio Signal Propagation Evaluation And Creating Statistical Models For Signal Strength Prediction In Differing Topographic Environments, Timothy Land

Electronic Theses and Dissertations

Radio wave signal strength and associated propagation models are rarely analyzed across individual geographic provinces. This study evaluates the effectiveness of the Radio Mobile model to predict radio wave signal strength in the Blue Ridge and Valley and Ridge physiographic provinces. A spectrum analyzer was used on 19 FM transmitters to determine model accuracy. Statistical analysis determined the significance between different terrain factors and signal strength. Field signal strength was found to be related to test site elevation, transmitter azimuth, elevation angle, transmitter elevation, path loss, and distance. Using 76 signal strength receiver sites, Ordinary Least Square regression models predicted …