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Physical Sciences and Mathematics Commons

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Statistics

Wright State University

2021

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Full-Text Articles in Physical Sciences and Mathematics

Computational Simulation And Analysis Of Neuroplasticity, Madison E. Yancey Jan 2021

Computational Simulation And Analysis Of Neuroplasticity, Madison E. Yancey

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Homeostatic synaptic plasticity is the process by which neurons alter their activity in response to changes in network activity. Neuroscientists attempting to understand homeostatic synaptic plasticity have developed three different mathematical methods to analyze collections of event recordings from neurons acting as a proxy for neuronal activity. These collections of events are from control data and treatment data, referring to the treatment of neuron cultures with pharmacological agents that augment or inhibit network activity. If the distribution of control events can be functionally mapped to the distribution of treatment events, a better understanding of the biological processes underlying homeostatic synaptic …


Bickel-Rosenblatt Test Based On Tilted Estimation For Autoregressive Models & Deep Merged Survival Analysis On Cancer Study Using Multiple Types Of Bioinformatic Data, Yan Su Jan 2021

Bickel-Rosenblatt Test Based On Tilted Estimation For Autoregressive Models & Deep Merged Survival Analysis On Cancer Study Using Multiple Types Of Bioinformatic Data, Yan Su

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This dissertation includes two topics, Bickel-Rosenblatt test based on tilted density estimation for autoregressive models and deep merged survival analysis on cancer study using multiple types of bioinformatic data. In the first topic study, we consider the goodness of fit test the error density of linear and nonlinear autoregressive models using tilted kernel density estimation based on residuals. Bickel-Rosenblatt test statistic is based on the integrated square error of non-parametric error density estimation and a smoothed version of the parametric fit of the density. It is shown that the new type of Bickel-Rosenblatt test statistics behaves asymptotically the same as …