Physical Sciences and Mathematics Commons^™

Machine Learning Analysis Of Single Nucleotide Polymorphism (Snp) Data To Predict Bone Mineral Density In African American Women, Erick Githua Wakayu

UNLV Theses, Dissertations, Professional Papers, and Capstones

Osteoporosis is a debilitating disease in which an individual’s bones weaken, making bones fragile and more susceptible to fracture. While commonly found amongst postmenopausal Caucasian and Asian women based on previous studies, those of African descent (African American/Black) have largely been ignored when it comes to osteoporotic studies, especially when it comes to Genome Wide Association Studies (GWAS). From GWA studies, we gain access to single nucleotide poly-morphisms (SNPs) that may contribute to certain illnesses, such as osteoporosis. With low Bone Mineral Density (BMD) being one of the primary markers of potential osteoporosis, it is prudent that proper research is …