Physical Sciences and Mathematics Commons^™

Novel Computational Methods For Transcript Reconstruction And Quantification Using Rna-Seq Data, Yan Huang

Theses and Dissertations--Computer Science

The advent of RNA-seq technologies provides an unprecedented opportunity to precisely profile the mRNA transcriptome of a specific cell population. It helps reveal the characteristics of the cell under the particular condition such as a disease. It is now possible to discover mRNA transcripts not cataloged in existing database, in addition to assessing the identities and quantities of the known transcripts in a given sample or cell. However, the sequence reads obtained from an RNA-seq experiment is only a short fragment of the original transcript. How to recapitulate the mRNA transcriptome from short RNA-seq reads remains a challenging problem. We …

Data Privacy Preservation In Collaborative Filtering Based Recommender Systems, Xiwei Wang

Theses and Dissertations--Computer Science

This dissertation studies data privacy preservation in collaborative filtering based recommender systems and proposes several collaborative filtering models that aim at preserving user privacy from different perspectives.

The empirical study on multiple classical recommendation algorithms presents the basic idea of the models and explores their performance on real world datasets. The algorithms that are investigated in this study include a popularity based model, an item similarity based model, a singular value decomposition based model, and a bipartite graph model. Top-N recommendations are evaluated to examine the prediction accuracy.

It is apparent that with more customers' preference data, recommender systems …

High Quality Human 3d Body Modeling, Tracking And Application, Qing Zhang

Theses and Dissertations--Computer Science

Geometric reconstruction of dynamic objects is a fundamental task of computer vision and graphics, and modeling human body of high fidelity is considered to be a core of this problem. Traditional human shape and motion capture techniques require an array of surrounding cameras or subjects wear reflective markers, resulting in a limitation of working space and portability. In this dissertation, a complete process is designed from geometric modeling detailed 3D human full body and capturing shape dynamics over time using a flexible setup to guiding clothes/person re-targeting with such data-driven models. As the mechanical movement of human body can be …

Privacy Preserving Data Mining For Numerical Matrices, Social Networks, And Big Data, Lian Liu

Theses and Dissertations--Computer Science

Motivated by increasing public awareness of possible abuse of confidential information, which is considered as a significant hindrance to the development of e-society, medical and financial markets, a privacy preserving data mining framework is presented so that data owners can carefully process data in order to preserve confidential information and guarantee information functionality within an acceptable boundary.

First, among many privacy-preserving methodologies, as a group of popular techniques for achieving a balance between data utility and information privacy, a class of data perturbation methods add a noise signal, following a statistical distribution, to an original numerical matrix. With the help …

Towards Intelligent Telerobotics: Visualization And Control Of Remote Robot, Bo Fu

Theses and Dissertations--Computer Science

Human-machine cooperative or co-robotics has been recognized as the next generation of robotics. In contrast to current systems that use limited-reasoning strategies or address problems in narrow contexts, new co-robot systems will be characterized by their flexibility, resourcefulness, varied modeling or reasoning approaches, and use of real-world data in real time, demonstrating a level of intelligence and adaptability seen in humans and animals. The research I focused is in the two sub-field of co-robotics: teleoperation and telepresence. We firstly explore the ways of teleoperation using mixed reality techniques. I proposed a new type of display: hybrid-reality display (HRD) system, which …

Consistency Checking Of Natural Language Temporal Requirements Using Answer-Set Programming, Wenbin Li

Theses and Dissertations--Computer Science

Successful software engineering practice requires high quality requirements. Inconsistency is one of the main requirement issues that may prevent software projects from being success. This is particularly onerous when the requirements concern temporal constraints. Manual checking whether temporal requirements are consistent is tedious and error prone when the number of requirements is large. This dissertation addresses the problem of identifying inconsistencies in temporal requirements expressed as natural language text. The goal of this research is to create an efficient, partially automated, approach for checking temporal consistency of natural language requirements and to minimize analysts' workload.

The key contributions of this …

Smooth Subdivision Surfaces: Mesh Blending And Local Interpolation, Jianzhong Wang

Theses and Dissertations--Computer Science

Subdivision surfaces are widely used in computer graphics and animation. Catmull-Clark subdivision (CCS) is one of the most popular subdivision schemes. It is capable of modeling and representing complex shape of arbitrary topology. Polar surface, working on a triangle-quad mixed mesh structure, is proposed to solve the inherent ripple problem of Catmull-Clark subdivision surface (CCSS).

CCSS is known to be C¹ continuous at extraordinary points. In this work, we present a G² scheme at CCS extraordinary points. The work is done by revising CCS subdivision step with Extraordinary-Points-Avoidance model together with mesh blending technique which selects guiding control …