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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

2015

Georgia Southern University

Department of Computer Science Faculty Publications

Differential

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Full-Text Articles in Physical Sciences and Mathematics

Entropyexplorer: An R Package For Computing And Comparing Differential Shannon Entropy, Kai Wang, Charles A. Philips, Arnold M. Saxton, Michael A. Langston Dec 2015

Entropyexplorer: An R Package For Computing And Comparing Differential Shannon Entropy, Kai Wang, Charles A. Philips, Arnold M. Saxton, Michael A. Langston

Department of Computer Science Faculty Publications

Background: Differential Shannon entropy (DSE) and differential coefficient of variation (DCV) are effective metrics for the study of gene expression data. They can serve to augment differential expression (DE), and be applied in numerous settings whenever one seeks to measure differences in variability rather than mere differences in magnitude. A general purpose, easily accessible tool for DSE and DCV would help make these two metrics available to data scientists. Automated p value computations would additionally be useful, and are often easier to interpret than raw test statistic values alone.

Results: EntropyExplorer is an R package for calculating DSE, DCV and …