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Full-Text Articles in Physical Sciences and Mathematics

The Behavior And Toxicity Of Metal Oxide Nanoparticles In Aqueous Solution, Phenny Mwaanga Dec 2012

The Behavior And Toxicity Of Metal Oxide Nanoparticles In Aqueous Solution, Phenny Mwaanga

All Dissertations

The dissolution and aggregation of metal oxides nanoparticles (NPs) in aqueous solution not only alter the abundance and toxicology of NPs, but also makes the effective assessment and the correct interpretation of effects of NPs on organisms challenging. The extent to which these processes (dissolution and aggregation) occur largely depend on pH, ionic strength, dissolved natural organic matter (NOM) and NPs characteristics. This study investigated the dissolution and aggregation behavior of the four metal oxide NPs (nZnO, nCuO, nFe2O3 and nTiO2) in aqueous solution as influenced by pH, ionic strength and NOM and examined the toxicity of these NPs to …


Ore And Gangue Mineral Paragenesis Of The Cortez Hills Carlin-Type Gold Deposit, Nevada: Evidence For Coincident High-Grade Gold Deposition And Collapse Brecciation, Lindsey R. Clark Dec 2012

Ore And Gangue Mineral Paragenesis Of The Cortez Hills Carlin-Type Gold Deposit, Nevada: Evidence For Coincident High-Grade Gold Deposition And Collapse Brecciation, Lindsey R. Clark

UNLV Theses, Dissertations, Professional Papers, and Capstones

The Cortez Hills Carlin-type gold deposit (CTGD), located on the Battle Mountain-Eureka trend of Northern NV, is hosted in a conical shaped polylithic breccia whose central axis strikes parallel to the imbricate Voodoo fault system. Gold grades at the center of the Cortez Hills Breccia Zone (CHBZ) are locally in excess of an ounce per ton. Gold mineralization within the refractory ore at Cortez Hills shares many characteristics with other well studied CTGDs. However, new observations during this study have recognized 1) fragmented realgar that are rimmed by gold-bearing iron-sulfide minerals in four samples, 2) a Hg- and Tl-rich late-ore …


An Analysis Of Drug Dissolution In Vivo, David Mcdonnell Jun 2012

An Analysis Of Drug Dissolution In Vivo, David Mcdonnell

Doctoral

The testing of drug dissolution rates from solid dosage forms is a very important area of research within the pharmaceutical industry. The ability to produce drugs with a given dissolution rate will lead to improved performance in the treatment of patients and will be of economic benefit to the pharmaceutical industry. However, dissolution testing in laboratories, aimed at reflecting in-vivo conditions, can be both time consuming and costly. Currently, most simulations of drug dissolution take place in standardized USP (United States Pharmaceutical) apparatuses. A number of these apparatuses exist, and it is the aim of this thesis to analyse drug …