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Full-Text Articles in Physical Sciences and Mathematics
Cost-Efficient Variable Selection Using Branching Lars, Li Hua Yue
Cost-Efficient Variable Selection Using Branching Lars, Li Hua Yue
Electronic Thesis and Dissertation Repository
Variable selection is a difficult problem in statistical model building. Identification of cost efficient diagnostic factors is very important to health researchers, but most variable selection methods do not take into account the cost of collecting data for the predictors. The trade off between statistical significance and cost of collecting data for the statistical model is our focus. A Branching LARS (BLARS) procedure has been developed that can select and estimate the important predictors to build a model not only good at prediction but also cost efficient. BLARS method is an extension of the LARS variable selection method to incorporate …
Survival Analysis Of Microarray Data With Microarray Measurement Subject To Measurement Error, Juan Xiong
Survival Analysis Of Microarray Data With Microarray Measurement Subject To Measurement Error, Juan Xiong
Electronic Thesis and Dissertation Repository
Microarray technology is essentially a measurement tool for measuring expressions of genes, and this measurement is subject to measurement error. Gene expressions could be employed as predictors for patient survival, and the measurement error involved in the gene expression is often ignored in the analysis of microarray data in the literature. Efforts are needed to establish statistical method for analyzing microarray data without ignoring the error in gene expression. A typical microarray data set has a large number of genes far exceeding the sample size. Proper selection of survival relevant genes contributes to an accurate prediction model. We study the …