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Articles 1 - 7 of 7
Full-Text Articles in Physical Sciences and Mathematics
Development Of A Carbon-Carbon Sandwich Composite With A Cellulose, Matt Brown
Development Of A Carbon-Carbon Sandwich Composite With A Cellulose, Matt Brown
Mahurin Honors College Capstone Experience/Thesis Projects
The development of a carbon-carbon sandwich composite with a cellulose derived core was developed and its properties investigated. This type of hybrid composite has never been made before. The goal was to combine the high temperature properties of carbon-carbon composites with the low weight of sandwich composites. In order to create a material with superior thermal properties and a high specific strength a carbon-carbon sandwich composite was developed utilizing a carbonized wood core. The composite was successfully constructed using an industrial grade carbon glue to hold two layers of carbon fiber weave on the top and bottom of the core. …
Modeling Thip;Ate Enzyme Chemistry With Cysteine At A High Ph, Emily Michelle Turner
Modeling Thip;Ate Enzyme Chemistry With Cysteine At A High Ph, Emily Michelle Turner
Mahurin Honors College Capstone Experience/Thesis Projects
Thiolate is a highly reactive species critical to the function of many enzymes. We attempted to model the chemistry of two of these enzymes with cysteine in solution at a high pH. To study cysteine proteases, we increased the pH of a cysteine and 4- nitrophenylacetate solution to create a visible color change when thiolyzed that was monitored through UV-Vis spectroscopy to determine rate constants. To study transferases, we attempted to model two reactions. The first was a methyl transfer from guanine to cysteine which mimicked O6-alkylguanine-DNA alkyltransferase. The second was activation of halogenated hydrocarbons by a mechanism similar to …
Streaming Fish Sampling: Abundance Versus Biomass Measurements And Determining A Minimum Number Of Years To Sample, Sarah B. Vied
Streaming Fish Sampling: Abundance Versus Biomass Measurements And Determining A Minimum Number Of Years To Sample, Sarah B. Vied
Mahurin Honors College Capstone Experience/Thesis Projects
Abundance and biomass are commonly used for estimating stream fish assemblage and community structure, yet questions arise whether one measurement contains more information about an assemblage and how long sampling should be. Principal component loadings derived from fish biomass measurements taken from Buck Creek in Allen County Kentucky were statistically compared to corresponding measures of abundance to test for significant differences in the two data sets. A sliding window analysis based on abundance was used to determine the minimum number of years a stream should be sampled. Abundance and biomass were not found to be significantly different; correlations of the …
A Comparison Of Cationic Surfactant Immobilized Ion Exchange Membranes In Their Application For Use In Extraction Of 4-Nitophenol, Robert Derrek Brown
A Comparison Of Cationic Surfactant Immobilized Ion Exchange Membranes In Their Application For Use In Extraction Of 4-Nitophenol, Robert Derrek Brown
Mahurin Honors College Capstone Experience/Thesis Projects
Solid Phase Extraction has replaced distillation and liquid-liquid extraction as the most widely used method for extraction from solution. Though traditional SPE has seen great success, its downfalls are that it requires meticulous preparation procedures requiring funtionalized silanes and silica or polymerization courses. An alternative is ion exchange membranes to which long carbon chain ionic surfactants have been attached. The S1000 membrane ion exchange capacity was measured to be approximately 110 micro-equil/disc while the P81 membrane was 150 micro-equil/disc. Octadecyltri-methylammonium surfactant was immobilized on the membrane surface, qualitated through the use of ATR-FTIR, and quantified through elemental analysis. Kinetic adsorption …
Scaling Of Feesing Behavior And Performance In The Goliath Grouper, Epinephelus Itajara, Michelle Riggs
Scaling Of Feesing Behavior And Performance In The Goliath Grouper, Epinephelus Itajara, Michelle Riggs
Mahurin Honors College Capstone Experience/Thesis Projects
Scaling is defined as the changes related to body size an animal undergoes during its life history. This change in body size can have implications for habitat use, prey consumed, and predatory threats, among others. The goliath grouper, Epinephelus itajara, undergoes one of the greatest amounts of scaling of any animal known, growing from 3mm at hatching to 2.3 m as adults. This tremendous change has implications for their development and niche as a top-level predator in their habitats. However, the consequences of their drastic change in body size for feeding performance have never been quantified. Here, a juvenile goliath …
Sythesis Of Carporide Derivatives For Sodium-Proton Exchange Inhibition, Jacob Adam Vervynckt
Sythesis Of Carporide Derivatives For Sodium-Proton Exchange Inhibition, Jacob Adam Vervynckt
Mahurin Honors College Capstone Experience/Thesis Projects
Over 200,000 people in the United States are diagnosed annually with malignant brain tumors. Current therapeutic methods prove ineffective at treating this type of cancer due to the inability to selectively target cancer cells. Research has shown that brain cancer cells are heavily dependent on the sodium-proton exchanger (NHE) and sodium-calcium exchanger (NCX) due to their increased metabolic activity. Inhibiting these proteins disrupts pH and ion balances within cancer cells while leaving healthy cells unaffected, leading to selective glial cell death. Therefore, NHE and NCX inhibition allow for selective targeting of brain cancer cells. The challenge that remains in using …
Reactions Of Cisplatin Analogs With Selenomethionine, Rebekkah Lively
Reactions Of Cisplatin Analogs With Selenomethionine, Rebekkah Lively
Mahurin Honors College Capstone Experience/Thesis Projects
Cisplatin is a well-known anti-cancer drug that is effective, but also has some severe and unwanted side effects. Analogs of cisplatin were reacted with the nonstandard amino acid selenomethionine (SeMet), and the products were characterized by 1H and 195Pt NMR spectroscopy and HPLC. In previous studies, SeMet was found to react faster than methionine (Met) with a representative platinum complex (Pt(dien)Cl2), therefore SeMet is said to react faster kinetically. Thus, while only a subset of proteins have selenium-containing amino acids, platinum complexes could target them kinetically. Cisplatin analogs with two leaving groups have also been studied. Pt(Me4en)(NO3)2 (Me4en = N,N,N’,N’-tetramethylethylenediamine) …