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Full-Text Articles in Physical Sciences and Mathematics

Electrodeposition Of Inorganic Materials With Tailored Shapes And Chiral Morphologies, Elizabeth A. Kulp Jan 2009

Electrodeposition Of Inorganic Materials With Tailored Shapes And Chiral Morphologies, Elizabeth A. Kulp

Doctoral Dissertations

"This dissertation investigates the electrodeposition of metal oxide films and biomaterial deposits on polycrystalline and single crystal substrates. Paper I describes the mechanisms and the characterization of an electrodeposited polycrystalline insulator, ceria (CeO₂), on Hastelloy substrates produced by the electrochemical oxidation of Ce(III) acetate complexes. In Paper II, epitaxial films of magnetite (Fe₃O₄) and ferrihydrite (Fe₁₀O₁₄(OH)₂) are deposited on gold single crystals. Paper III reports the electrodeposition of epitaxial Fe₃O₄ and zinc ferrite (ZnFe₂O₄) periodic nanostructures known as superlattices by pulsing between two potentials. Papers IV and V describe chiral electrodeposition. In Paper IV, epitaxial, chiral orientations of cupric oxide …


Investigation Of The Interactions Between Selected Nanoparticles And Human Lung Carcinoma Cells At The Single Cell And Single Particle Level, Isaac Stayton Jan 2009

Investigation Of The Interactions Between Selected Nanoparticles And Human Lung Carcinoma Cells At The Single Cell And Single Particle Level, Isaac Stayton

Doctoral Dissertations

"The recent advances in nanomaterials development and applications have sparked concerns regarding the safety of these materials in living organisms. This body of work investigates specific interactions between chosen nanoparticles and living human lung carcinoma (A549) cells"--Abstract, page iv.


A Study Of The Beneficial Role Of Thiol Antioxidant Supplementation In Various Forms Of Glutathione Deficiency, Linu Sara Abraham Jan 2009

A Study Of The Beneficial Role Of Thiol Antioxidant Supplementation In Various Forms Of Glutathione Deficiency, Linu Sara Abraham

Doctoral Dissertations

"Oxidative stress plays a major role in the pathology of numerous disorders afflicting humans, ranging from neurodegenerative diseases, to cancer, and heavy metal toxicity. Scientists are on the constant lookout for new and better antioxidants that have the ability to slow, if not stop the harmful degenerative effects of free radicals in oxidative stress related disorders. Both synthetic and naturally occurring compounds are being constantly screened for their antioxidant properties. This study attempted to evaluate the abilities of a thiol antioxidant, N-Acetylcysteine amide (NACA), to protect cells from the harmful effects of glutathione depletion in two different models of oxidative …


F₂-Isoprostanes Study After Exposure To Selected Nanoparticles By Liquid Chromatography/Tandem Mass Spectrometry And Investigation Of Nanoparticles On The Cytotoxicity Effect Of Arsenic In Vitro, Xiaoqian Liu Jan 2009

F₂-Isoprostanes Study After Exposure To Selected Nanoparticles By Liquid Chromatography/Tandem Mass Spectrometry And Investigation Of Nanoparticles On The Cytotoxicity Effect Of Arsenic In Vitro, Xiaoqian Liu

Doctoral Dissertations

"Nanopartices as a new class of materials found their applications in industry, aerospace, clinical diagnosis and cancer therapy. Recently, the health effects of nanoparticles have caused people great concerns. This dissertation studies the mechanisms of nanoparticle cytotoxicity in human lung epithelial cells (A549). F₂-isoprostanes are novel reliable biomarkers for lipid peroxidation. In the first part of this work, total free F₂-isoprostanes were quantified by high performance liquid chromatography/mass spectrometry followed by the exposure of SiO₂ (15 nm), CeO₂ (20 nm), Fe₂O₃ (30 nm), and ZnO (70 nm) nanoparticles for 24 hours. For the first time, the results showed that F₂-isoprostanes …