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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Predicting Coronary Artery Disease With Medical Profile And Gene Polymorphisms Data, Qiongyu Chen, Guoliang Li, Tze-Yun Leong, Chew-Kiat Heng Aug 2007

Predicting Coronary Artery Disease With Medical Profile And Gene Polymorphisms Data, Qiongyu Chen, Guoliang Li, Tze-Yun Leong, Chew-Kiat Heng

Research Collection School Of Computing and Information Systems

Coronary artery disease (CAD) is a main cause of death in the world. Finding cost-effective methods to predict CAD is a major challenge in public health. In this paper, we investigate the combined effects of genetic polymorphisms and non-genetic factors on predicting the risk of CAD by applying well known classification methods, such as Bayesian networks, naïve Bayes, support vector machine, k-nearest neighbor, neural networks and decision trees. Our experiments show that all these classifiers are comparable in terms of accuracy, while Bayesian networks have the additional advantage of being able to provide insights into the relationships among the variables. …


Century: Automated Aspects Of Patient Care, Marion Blount, John Davis, Maria Ebling, Ji Hyun Kim, Kyun Hyun Kim, Kang Yoon Lee, Archan Misra, Se Hun Park, Daby Sow, Young Ju Tak, Min Wang, Karen Witting Aug 2007

Century: Automated Aspects Of Patient Care, Marion Blount, John Davis, Maria Ebling, Ji Hyun Kim, Kyun Hyun Kim, Kang Yoon Lee, Archan Misra, Se Hun Park, Daby Sow, Young Ju Tak, Min Wang, Karen Witting

Research Collection School Of Computing and Information Systems

Remote health monitoring affords the possibility of improving the quality of health care by enabling relatively inexpensive out-patient care. However, remote health monitoring raises new a problem: the potential for data explosion in health care systems. To address this problem, the remote health monitoring systems must be integrated with analysis tools that provide automated trend analysis and event detection in real time. In this paper, we propose an overview of Century, an extensible framework for analysis of large numbers of remote sensor-based medical data streams.


Learning Causal Models For Noisy Biological Data Mining: An Application To Ovarian Cancer Detection, Ghim-Eng Yap, Ah-Hwee Tan, Hwee Hwa Pang Jul 2007

Learning Causal Models For Noisy Biological Data Mining: An Application To Ovarian Cancer Detection, Ghim-Eng Yap, Ah-Hwee Tan, Hwee Hwa Pang

Research Collection School Of Computing and Information Systems

Undetected errors in the expression measurements from highthroughput DNA microarrays and protein spectroscopy could seriously affect the diagnostic reliability in disease detection. In addition to a high resilience against such errors, diagnostic models need to be more comprehensible so that a deeper understanding of the causal interactions among biological entities like genes and proteins may be possible. In this paper, we introduce a robust knowledge discovery approach that addresses these challenges. First, the causal interactions among the genes and proteins in the noisy expression data are discovered automatically through Bayesian network learning. Then, the diagnosis of a disease based on …


A Time-And-Value Centric Provenance Model And Architecture For Medical Event Streams, Marion Bllount, John Davis, Archan Misra, Daby Sow, Min Wang Jun 2007

A Time-And-Value Centric Provenance Model And Architecture For Medical Event Streams, Marion Bllount, John Davis, Archan Misra, Daby Sow, Min Wang

Research Collection School Of Computing and Information Systems

Provenance becomes a critical requirement for healthcare IT infrastructures, especially when pervasive biomedical sensors act as a source of raw medical streams for large-scale, automated clinical decision support systems. Medical and legal requirements will make it obligatory for such systems to answer queries regarding the underlying data samples from which output alerts are derived, the IDs of the processing components used and the privileges of the individuals and software components accessing the medical data. Unfortunately, existing models of either annotation or process based provenance are designed for transaction-oriented systems and do not satisfy the unique requirements for systems processing high-volume, …