Physical Sciences and Mathematics Commons^™

Numerical Simulation And Graphical Analysis Of In Vitro Benign Tumor Growth: Application Of Single-Particle State Bosonic Matter Equation With Length Scaling, Pradip K. Biswas, Jiansen Niu, Tobias Frederico, Valentin Gogonea

Chemistry Faculty Publications

We describe the application of a non-linear single-particle state bosonic condensate equation to simulate multicellular tumor growth by treating it as a coupling of two classical wave equations with real components. With one component representing the amplitude of the cells in their volume growth phase and the other representing the amplitude of the cells in their proliferation or mitosis phase, the two components of the coupled equation feed each other during the time evolution and are coupled together through diffusion and other linear and non-linear terms. The features of quiescent and necrotic cells, which result from poor nutrient diffusion into …

Bounded Search For De Novo Identification Of Degenerate Cis-Regulatory Elements, Jonathan M. Carlson, Arijit Chakravarty, Radhika S. Khetani, Robert H. Gross

Dartmouth Scholarship

The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential cis-regulatory elements. However, in practice many cis-regulatory elements are highly degenerate, precluding the use of an exhaustive word-counting strategy for their identification. While numerous methods exist for inferring base distributions using a position weight matrix, recent studies suggest that the independence assumptions inherent in the model, as well as the inability to reach a global optimum, limit this approach.

A Comparative Analysis Of Air-To-Ground Engagement Outcomes In The Joint Warfare System (Jwars) And The Jwars-Joint Semi-Automated Forces Federation, Melissa Anne St. Peter

Computational Modeling & Simulation Engineering Theses & Dissertations

Multi-resolution modeling is the process by which a single model is created by connecting multiple individual models to describe phenomena at different levels of resolution [1]. "When we change resolutions, replacing a detailed model by a more aggregate one, we must ask whether results are 'consistent'" [2].

There are many methods of determining if the results of two simulations are 'consistent'. However, they are very entailed and require a detailed understanding of the individual models including their functionality, algorithms, and inner workings. A straight forward and rapid way of assessing potential inconsistencies is through a statistical comparison of the model …

Loop Current Warming By Hurricane Wilma, Lie-Yauw Oey, Tal Ezer, Dong-Ping Wang, S. J. Fan, Xun-Qiang Yin

CCPO Publications

Hurricanes mix and cool the upper ocean, as shown here in observations and modeling of the Caribbean Sea and the Gulf of Mexico during the passage of hurricane Wilma. Curiously, the upper ocean around the Loop Current warmed prior to Wilma's entrance into the Gulf. The major cause was increased volume and heat transports through the Yucatan Channel produced by storm-induced convergences in the northwestern Caribbean Sea. Such oceanic variability may have important impacts on hurricane predictions.

Topographic Influence On Overflow Dynamics: Idealized Numerical Simulations And The Faroe Bank Channel Overflow, Tal Ezer

CCPO Publications

Properties of the North Atlantic Deep Water (NADW) depend on mixing that occurs in the Denmark Strait (DS) and the Faroe Bank Channel (FBC) overflow regions. How the sill's topography in those regions may affect mixing processes and downstream variability is thus investigated using a high-resolution terrain-following ocean model. Model results agree with observations that show enhanced mixing and entrainment downstream from the sill; however, mixing seems to occur over a longer distance downstream from the FBC sill and more abruptly downstream from the DS sill. Sensitivity experiments with various FBC sill widths demonstrate that the narrow sill is responsible …

Design Factors For The Communication Architecture Of Distributed Discrete Event Simulation Systems, Catharine Mcintire Hoaglund

Theses Digitization Project

The purpose of the thesis was to investigate the influence communication architecture decisions have on the performance of a simulation system with distributed components. In particular, the objective was to assess the relative importance of factors affecting reliability and variability of an external data interface to the performance of the simulation, as compared to factor within the simulation itself.