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Full-Text Articles in Physical Sciences and Mathematics
The Use Of Fluorescence To Investigate The Factors Leading To Complex Formation Between Naphthalenes And ├Ƒ-Cyclodextrins, Jamie M. Iannacone
The Use Of Fluorescence To Investigate The Factors Leading To Complex Formation Between Naphthalenes And ├Ƒ-Cyclodextrins, Jamie M. Iannacone
Honors Theses
Fraiji et al. determined a binding constant (K) of 581 = 6 M-1 for the 1:1 complex between 2-acetylnaphthalene (2-AN) and β-cyclodextrin (β-CD) in H20 using fluorescence quenching experiments (Appl. Spectrosc. 1994, 48, 79). Molecular modeling experiments indicate the possibility of complex stabilization resulting from hydrogen bonds between the C=O group of 2-AN and the -OH groups on the rim of β-CD. To check this possibility, we measured the K of the 2-AN:trimethyl-β-CD (TM-β- CD) complex, where all rim -OH groups are converted to –OCH3. In this case, K decreases to 134 M-1. To show that this is due to …
Sol-Gel-Platform Optical Sensors For Oxygen Gas : Sensor Development And Investigation Of Probe Partitioning In Sol-Gel Matrices, Desiree L. Plata
Sol-Gel-Platform Optical Sensors For Oxygen Gas : Sensor Development And Investigation Of Probe Partitioning In Sol-Gel Matrices, Desiree L. Plata
Honors Theses
I have developed gas sensors that respond rapidly and noticeably to changes in oxygen concentration by doping fluorescent complexes into gas-permeable sol-gel materials. Ruthenium (II) 4,7-diphenyl-1,10- phenanthroline, Ru(dpp)32+, responds to variations in ambient oxygen concentrations through marked changes in its fluorescence intensity. I investigated the response of Ru(dpp)32+ to oxygen in solution, in aerogels (sol gels dried under ambient conditions) and in aerogels (sol gels dried using supercritical conditions). Aerogels have particularly high porosity and low density, which allows for rapid diffusion of gases into the material. The aerogel sensor responds reversibly to changes in ambient oxygen concentration within 10 …
Investigation Of Indicators In Aerogels And Xerogels, Rebecca L. Wolfe
Investigation Of Indicators In Aerogels And Xerogels, Rebecca L. Wolfe
Honors Theses
A sol-gel is a silicon-oxygen matrix that is suitable for the entrapment of chemical species, including biological species, indicators, dyes, and sensors. Aerogels are sol-gels prepared by supercritical extraction, whereas aerogels are allowed to dry under ambient conditions. The resulting materials differ considerably in their physical properties. We are investigating a series of luminescent species for use as probes of the microenvironment in different sol-gel materials. Sol gels containing each probe are prepared as both aerogels and aerogels; aerogels are formed using a novel contained mold process. Spectral properties, including absorption or excitation spectra, emission spectra, time-based fluorescence scans, and …
Solution Structure Refinement Comparing Reference Model Noe Volumes, Maura Mahar
Solution Structure Refinement Comparing Reference Model Noe Volumes, Maura Mahar
Honors Theses
NMR is a powerful experimental technique which can be used to determine protein structures. Central to this process is conversion of peak volumes in the NOE data sets into distance constraints and then structural refinement against those constraints. In general, each solution structural analysis is initiated de novo. We are interested in the structural analysis of a series of hybrids derived from two parental proteins (rubredoxins from mesophilic bacterium Clostridium pasteurianum (Cp) and the hyperthermophilic archaeon Pyrococcus furiosus (Pf)). Near 1 A resolution X-ray structures of Cp and Pf rubredoxins are available to provide a basis for quantitative comparison of …